Tacrolimus FDA Link Generic

A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.

Also Known As:

Prograf; Anhydrous Tacrolimus; FK-506; FK506; FR-900506; Prograft; Tacrolimus Anhydrous; Anhydrous, Tacrolimus; FK 506; FR 900506; FR900506; Tacrolimus, Anhydrous; 15,19- Epoxy- 3H- pyrido(2,1- c)(1,4)oxaazacyclotricosine- 1,7,20,21(4H,23H)- tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a- hexadecahydro- 5,19- dihydroxy- 3- (2- (4- hydroxy- 3- methoxycyclohexyl)- 1- methylethenyl)- 14,16- dimethoxy- 4,10,12,18- tetramethyl- 8- (2- propenyl)- , monohydrate, (3S- (3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-

Pharmalogical Action Categories:

Calcineurin Inhibitors
Immunosuppressive Agents

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - Tacrolimus: 7819

C24-deoxyascomycin

Bio-Agent Context: Research Results