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99mTc(HYNICtide)(tricine)(TPPTS)

structure in first source

Also Known As:

RP 444; RP-444; RP444

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - 99mTc(HYNICtide)(tricine)(TPPTS): 3
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - 99mTc(HYNICtide)(tricine)(TPPTS): 3
Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organotechnetium Compounds: 1
    - 99mTc(HYNICtide)(tricine)(TPPTS): 3

Experts

1.	Baidouri, Hasna: 1 article (12/2017)
2.	Clemens, L Edward: 1 article (12/2017)
3.	Hanlon, Samuel: 1 article (12/2017)
4.	Jaynes, Jesse: 1 article (12/2017)
5.	Kolar, Satya S: 1 article (12/2017)
6.	Lim, Edward: 1 article (12/2017)
7.	McDermott, Alison M: 1 article (12/2017)
8.	Reins, Rose Y: 1 article (12/2017)
9.	Woodburn, Kathryn W: 1 article (12/2017)
10.	Diluzio, W R: 1 article (02/2001)

Related Diseases

1.	Thrombosis (Thrombus) 02/01/2001 - "Towards developing a non-SnCl2 formulation for RP444, a new radiopharmaceutical for thrombus imaging." 09/01/1999 - "Eight HYNICtide hydrazones (three with aliphatic substituents and five with aromatic groups) were studied for their potential use as the final intermediate for preparation of RP444, a new radiopharmaceutical under development for imaging thrombosis. "
2.	Keratitis 12/01/2017 - "RP444 demonstrated significant efficacy in a murine model of bacterial keratitis as evidenced by a significant dose-dependent decrease in ocular clinical scores, a significantly reduced bacterial load, and substantially decreased inflammatory cell infiltrates. " 12/01/2017 - "The most active dHDP, RP444, was evaluated for propensity to induce drug resistance and therapeutic benefit in a murine Pseudomonas aeruginosa keratitis model. "

Related Drugs and Biologics

1.	Radiopharmaceuticals
2.	Hydrazones