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(R)- 2- (4'- bromo- biphenyl- 4- sulfonyl- amino)- 3- methyl- butyric acid

Also Known As:

PD 166793; PD 169469; PD-166793; PD166793

Networked: 6 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Hydroxamic Acids: 239
      - (R)-2-(4'-bromo-biphenyl-4-sulfonyl-amino)-3-methyl-butyric acid: 6
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Hydroxamic Acids: 239
      - (R)-2-(4'-bromo-biphenyl-4-sulfonyl-amino)-3-methyl-butyric acid: 6
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - (R)-2-(4'-bromo-biphenyl-4-sulfonyl-amino)-3-methyl-butyric acid: 6

Experts

1.	Ertl, Georg: 1 article (01/2016)
2.	Frantz, Stefan: 1 article (01/2016)
3.	Frey, Anna: 1 article (01/2016)
4.	Hofmann, Ulrich: 1 article (01/2016)
5.	Lehmann, Marc: 1 article (01/2016)
6.	Lesch, Klaus-Peter: 1 article (01/2016)
7.	Mathes, Denise: 1 article (01/2016)
8.	Pachel, Christina: 1 article (01/2016)
9.	Popp, Sandy: 1 article (01/2016)
10.	Saxon, Veronica-Maria: 1 article (01/2016)

Related Diseases

1.	Rupture 01/01/2016 - "Pretreatment with the MMP inhibitor PD 166793 prevented left ventricular ruptures and demonstrated a tendency to improved survival after citalopram treatment. "
2.	Heart Failure 01/01/2008 - "Inhibiting metalloproteases with PD 166793 in heart failure: impact on cardiac remodeling and beyond." 05/08/2001 - "LV size and function were measured in 5 groups of rats: (1) obese male spontaneously hypertensive heart failure rats (SHHF) at 9 months (n=10), (2) SHHF at 13 months (n=12), (3) SHHF rats treated with an MMP inhibitor during months 9 to 13 (PD166793 5 mg. kg(-1). " 04/23/2002 - "Accordingly, this study focused on the effects of MMP inhibition therapy (PD 166793, 1 mg x kg(-1) x d(-1)) on LV size and function in a rat model of volume overload-induced heart failure. "
3.	Neoplasm Metastasis (Metastasis) 01/01/2005 - "Furthermore, we were able to significantly decrease the development of breast cancer brain metastasis in animals by treatment with PD 166793, a selective synthetic MMP inhibitor. "
4.	Infarction (Infarctions) 03/01/2003 - "At 5 days after infarction, the pigs were randomized to undergo broad-spectrum matrix metalloproteinase inhibition (n = 9; PD166793, 20 mg. kg(-1). "
5.	Breast Neoplasms (Breast Cancer) 01/01/2005 - "Furthermore, we were able to significantly decrease the development of breast cancer brain metastasis in animals by treatment with PD 166793, a selective synthetic MMP inhibitor. "

Related Drugs and Biologics

1.	Matrix Metalloproteinase Inhibitors
2.	Citalopram
3.	Matrix Metalloproteinases (MMPs)
4.	Metalloproteases (Metalloproteinases)

Related Therapies and Procedures

1.	Therapeutics