micafungin (FK463)

02/01/2015 - "The aim of this analysis was to identify therapeutic micafungin regimens for children that produce the same micafungin exposures known to be effective for the prevention and treatment of Candida infections in adults. "
06/01/2013 - "Micafungin (MCFG) is an antifungal agent that is widely used for the treatment of invasive fungal infection. "
04/01/2011 - "Micafungin, a newly developed echinocandin-type antifungal agent, is widely used for the treatment of deep-seated fungal infections including those of Candida species and Aspergillus species. "
02/01/2006 - "Micafungin may prove useful in the treatment of infections due to azole-resistant Candida."
04/01/2005 - "These results warrant future studies on the efficacy of micafungin ophthalmic solution against corneal fungal infection."

12/01/2015 - "Intermittent Dosing of Micafungin Is Effective for Treatment of Experimental Disseminated Candidiasis in Persistently Neutropenic Rabbits."
04/01/2009 - "Efficacy of micafungin in treating four premature infants with candidiasis."
03/01/2000 - "The efficacy of FK463 was also evaluated in the disseminated candidiasis target organ assay and was compared with those of FLCZ and AMPH-B. "
12/01/2015 - "To improve quality of life, reduce costs, and improve outcome, we studied the pharmacokinetics (PK), efficacy, and safety of alternate dosing regimens of micafungin (MFG) for the treatment of experimental subacute disseminated candidiasis. "
03/01/2015 - "For micafungin, AUC-to-minimum inhibitory concentration (AUC/MIC) ratios have a close deterministic relationship with efficacy in candidiasis; an AUC/MIC ≥3,000 is associated with 98% efficacy. "

11/01/2006 - "This study evaluated the safety and efficacy of micafungin in patients with proven or probable invasive aspergillosis (IA). "
04/01/2003 - "We tested the efficacy of micafungin (FK) alone or in combination with other antifungals against systemic murine aspergillosis. "
04/01/2003 - "Efficacy of micafungin alone or in combination against systemic murine aspergillosis."
01/01/2015 - "The objective of this study was to evaluate the efficacy and safety of micafungin as salvage monotherapy in patients with invasive aspergillosis. "
01/01/2015 - "Randomised, multicentre trial of micafungin vs. an institutional standard regimen for salvage treatment of invasive aspergillosis."

03/31/2009 - "Micafungin is safe and effective in the treatment of children and adults with invasive candidiasis. "
02/01/2014 - "Efficacy of micafungin in invasive candidiasis caused by common Candida species with special emphasis on non-albicans Candida species."
01/01/2014 - "A multicenter observational study was conducted in Italy to assess the safety of micafungin in the daily clinical practice for the treatment of proven and suspected invasive candidiasis (IC), as well as to describe rates of clinical response to micafungin treatment. "
01/01/2014 - "Micafungin for the treatment of proven and suspected invasive candidiasis in children and adults: findings from a multicenter prospective observational study."
03/31/2009 - "Althought the European Medicines Agency approved in 2008 the use of Micafungin for the treatment of invasive candidiasis in children, the available clinical experience is limited and currently more clinical studies are warranted to define its efficacy and safety in neonates."

11/01/2003 - "Micafungin is effective against candidemia due to C. "
10/01/2005 - "Micafungin shows promise as a safe and effective agent for the treatment of newly diagnosed and refractory cases of candidemia. "
04/01/2005 - "It is suggested that micafungin is useful for the treatment of candidemia associated with Candida parapsilosis."
10/01/2005 - "Efficacy of micafungin for the treatment of candidemia."
01/01/2014 - "Thus, based on the results of the present study, the optimal micafungin dose for the treatment of candidemia appears to range from 100 to 150 mg/d, as recommended by the Guidelines."