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L 779976

a somatostatin 2 receptor agonist

Also Known As:

L 779,976; L-779,976; L779976

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - L 779976: 2
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - L 779976: 2

Experts

1.	Aourz, Najat: 1 article (12/2011)
2.	Clinckers, Ralph: 1 article (12/2011)
3.	De Bundel, Dimitri: 1 article (12/2011)
4.	Michotte, Yvette: 1 article (12/2011)
5.	Portelli, Jeanelle: 1 article (12/2011)
6.	Smolders, Ilse: 1 article (12/2011)
7.	Stragier, Bart: 1 article (12/2011)
8.	Aliprandi, M: 1 article (09/2002)
9.	Billard, J M: 1 article (09/2002)
10.	Carlo, A S: 1 article (09/2002)

Related Diseases

1.

Seizures (Absence Seizure)

12/01/2011 - "Using microdialysis and telemetry-based electroencephalographic recordings we show that intrahippocampal administration of the sst(2) agonist L-779,976 (500 nM), the sst(3) agonist L-796,778 (100 nM) or the sst(4) agonist L-803,087 (100 nM) protects rats against focal pilocarpine-induced seizures. "
09/01/2002 - "Intrahippocampal injection of three selective sst2 receptor agonists in wild-type mice (Octreotide, BIM 23120 and L-779976, 1.5-6.0 nmol) did not affect kainate seizures while the same compounds significantly reduced seizures in rats. "

Related Drugs and Biologics

1.	Octreotide (Sandostatin)
2.	Pilocarpine (Ocusert)
3.	Kainic Acid (Kainate)
4.	BIM 23120
5.	L803087
6.	L796778