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KD3 671

structure in first source

Also Known As:

2-propyl-8-oxo-1-((2'-(H-tetrazole-5-yl)biphenyl-4-yl)methyl)-4,5,6,7,8-tetrahydro-cycloheptimidazole; KD3-671

Networked: 5 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - KD3 671: 5
    - Tetrazoles: 14
      - KD3 671: 5

Experts

1.	Nagamatsu, Tadashi: 2 articles (06/2003 - 02/2002)
2.	Nagao, Toshiyuki: 2 articles (06/2003 - 02/2002)
3.	Suzuki, Yoshio: 2 articles (06/2003 - 02/2002)
4.	Oka, Tatsuya: 1 article (06/2003)
5.	Hayashi, Kazumi: 1 article (02/2002)
6.	Iga, T: 1 article (01/2001)
7.	Ito, K: 1 article (01/2001)
8.	Matsuo, H: 1 article (01/2001)
9.	Miyamoto, H: 1 article (01/2001)
10.	Sawada, Y: 1 article (01/2001)

Related Diseases

1.	Glomerulonephritis 06/01/2003 - "These findings suggest that KD3-671 may be an effective agent for the treatment of mesangioproliferative glomerulonephritis." 06/11/1999 - "These results suggest that KD3-671 may be a useful medicine against glomerulonephritis and glomerulosclerosis." 06/01/2003 - "We examined the effects of KD3-671 (2-propyl-8-oxo-1-[(2'-(H-tetrazole-5-yl)biphenyl-4-yl)methyl]-4,5,6,7-tetrahydrocycloheptimidazole), an angiotensin II type1 receptor antagonist, on an experimental rat model of mesangioproliferative glomerulonephritis, anti-Thy-1 nephritis. "
2.	Hypertension (High Blood Pressure) 11/01/1998 - "These results suggest that KD3-671 may be useful for the treatment of hypertension."
3.	Proteinuria 02/01/2002 - "KD3-671 (30 mg/kg per day) inhibited the elevation of proteinuria and plasma total cholesterol. " 06/11/1999 - "Administration of KD3-671 to nephritic rats prevented the development of intense proteinuria, glomerular alterations and the increase in plasma urea nitrogen. "
4.	Nephritis 06/01/2003 - "Effects of KD3-671, an angiotensin II type 1 receptor antagonist, on anti-thy-1 nephritis in rats." 06/11/1999 - "We investigated the effects of KD3-671, an angiotensin AT1 receptor antagonist (2-propyl-8-oxo-1-[(2'-(H-tetrazole-5-yl)biphenyl-4-yl)methyl]-4,5,6,7-t etrahydro-cycloheptimidazole), on anti-glomerular basement membrane antibody-associated nephritis in rats. " 06/01/2003 - "We examined the effects of KD3-671 (2-propyl-8-oxo-1-[(2'-(H-tetrazole-5-yl)biphenyl-4-yl)methyl]-4,5,6,7-tetrahydrocycloheptimidazole), an angiotensin II type1 receptor antagonist, on an experimental rat model of mesangioproliferative glomerulonephritis, anti-Thy-1 nephritis. "
5.	Membranous Glomerulonephritis (Membranous Nephropathy) 02/01/2002 - "KD3-671 had an antiproteinuric effect in rats with accelerated passive Heymann nephritis. " 02/01/2002 - "Antiproteinuric effect of KD3-671, an angiotensin II type 1 receptor antagonist, in rats with accelerated passive Heymann nephritis." 02/01/2002 - "The antiproteinuric effect of KD3-671 (2-propyl-8-oxo-1-[(2'-(H-tetrazole-5-yl)biphenyl-4-yl)methyl]-4,5,6,7-tetrahydrocycloheptimidazole), an angiotensin II type 1 receptor antagonist, was compared with that of enalapril, an angiotensin 11-converting enzyme inhibitor, using an experimental model of membranous nephropathy. "

Related Drugs and Biologics

1.	1H-tetrazole (tetrazole)
2.	diphenyl (biphenyl)
3.	Angiotensin II Type 1 Receptor Blockers
4.	Angiotensin Receptor Antagonists
5.	Type 1 Angiotensin Receptor
6.	Enalaprilat (Vasotec)
7.	Urea (Carbamide)
8.	Nitrogen
9.	Enzyme Inhibitors (Inhibitors, Enzyme)
10.	Enalapril