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tabimorelin

a growth hormone secretagogue; structure in first source

Also Known As:

NN 703; NN-703

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - tabimorelin: 1

Experts

1.	Ahnfelt-Rønne, I: 1 article (06/2004)
2.	Holm, A M: 1 article (06/2004)
3.	Johansen, P B: 1 article (06/2004)
4.	Rømer, J: 1 article (06/2004)

Related Diseases

1.	Hyperphagia (Overeating) 06/01/2004 - "Tabimorelin treatment induced hyperphagia and adiposity (increased total fat mass and gain in body weight) in lean control rats, while these parameters were not increased in ZDF rats. " 06/01/2004 - "The elimination of tabimorelin-induced adiposity and hyperphagia in ZDF rats may be due to lack of POMC mRNA downregulation. " 06/01/2004 - "This shows that tabimorelin-induced adiposity and hyperphagia in lean control rats are correlated with increased hypothalamic NPY mRNA and decreased POMC mRNA expression. "
2.	Body Weight (Weight, Body) 06/01/2004 - "Tabimorelin treatment induced hyperphagia and adiposity (increased total fat mass and gain in body weight) in lean control rats, while these parameters were not increased in ZDF rats. " 06/01/2004 - "Leptin-receptor mutated Zucker diabetic fatty (ZDF) and lean control rats were treated with the ghrelin-receptor ligand, tabimorelin (50 mg/kg p.o.) for 18 days, and the effects on body weight, food intake and body composition were investigated. "

Related Drugs and Biologics

1.	Ghrelin Receptors
2.	Leptin Receptors
3.	Messenger RNA (mRNA)
4.	Pro-Opiomelanocortin (Proopiomelanocortin)
5.	Ligands