CB 1267

structure in first source

Also Known As:

1(S),3(R)-dihydroxy-20(R)-(4-hydroxy-4-trifluoromethyl-5,5-5-trif-luoro-1-pent-2-ynyloxymethyl)-9,10-sero-pregna-5(Z),7(E),10(19)-triene-alpha,25(OH)2D3; CB-1267; CB1267

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

Prostatic Neoplasms (Prostate Cancer)

08/01/1999 - "Combination of a new vitamin D3 analog (CB1267) and a retinoid (9-cis-RA) potently inhibited colony formation of LNCaP prostate cancer cells in vitro, suggesting further studies in animal models. "
08/01/1999 - "We examined the ability of four novel 20-epi-vitamin D3 analogs (CB1093, KH1060, KH1266, and CB1267), either alone or in combination with 9-cis retinoic acid (RA) to inhibit colony growth of a human prostate cancer cell line, LNCaP, using soft agar as well as bone marrow stroma. "

Related Drugs and Biologics

1.	Retinoids
2.	Cholecalciferol (Vitamin D3)
3.	Tretinoin (Retinoic Acid)
4.	Agar
5.	KH 1060