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trocarin

a prothrombin activator from Tropidechis carinatus venom; amino acid sequence in first source

Also Known As:

trocarin, venom

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzyme Precursors: 724
  - Prothrombin: 5251
    - trocarin: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Prothrombin: 5251
        trocarin: 1
  - Protein Precursors: 37
    - Enzyme Precursors: 724
      - Prothrombin: 5251
        trocarin: 1
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Prothrombin: 5251
    - trocarin: 1

Experts

1.	Joseph, Jeremiah S: 1 article (12/2003)
2.	Kini, R Manjunatha: 1 article (12/2003)
3.	Thirumangalathu, Shoba: 1 article (12/2003)
4.	Tsang, Fai: 1 article (12/2003)
5.	Wong, Fred W S: 1 article (12/2003)

Related Diseases

1.	Inflammation (Inflammations) 12/01/2003 - "Here we show that, interestingly, trocarin also causes edema in the mouse footpad; the inflammation, accompanied by a large purplish clot, is more persistent than the transient edema caused by FXa. " 12/01/2003 - "Hence trocarin, being closely related to FXa, has similar non-hemostatic functions in mediating inflammation and mitogenesis, yet appears to act by distinctly different mechanisms." 12/01/2003 - "Moreover, trocarin-induced edema is not inhibited by a synthetic peptide based on the FXa-binding region of EPR-1, indicating that the inflammation is probably mediated by a mechanism independent of EPR-1-binding. " 12/01/2003 - "Trocarin, a blood coagulation factor Xa homologue from snake venom, causes inflammation and mitogenesis."
2.	Edema (Dropsy) 12/01/2003 - "Histological examination indicates significant differences between edema induced by FXa and trocarin. " 12/01/2003 - "Here we show that, interestingly, trocarin also causes edema in the mouse footpad; the inflammation, accompanied by a large purplish clot, is more persistent than the transient edema caused by FXa. " 12/01/2003 - "Moreover, trocarin-induced edema is not inhibited by a synthetic peptide based on the FXa-binding region of EPR-1, indicating that the inflammation is probably mediated by a mechanism independent of EPR-1-binding. "

Related Drugs and Biologics

1.	Snake Venoms (Snake Venom)
2.	Peptides (Polypeptides)
3.	Hemostatics (Antihemorrhagics)
4.	Blood Coagulation Factors (Coagulation Factor)