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KF 25706
a derivative of radicicol; structure in first source
Also Known As:
KF25706
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Lactones: 1549
KF 25706: 1
Related Diseases
1.
Neoplasms (Cancer)
06/15/1999 - "
Because radicicol lacks antitumor activity in vivo in experimental animal models, we examined the antitumor activity of a novel radicicol oxime derivative, radicicol 6-oxime (KF25706), on human tumor cell growth both in vitro and in vivo.
"
2.
Carcinoma (Carcinomatosis)
06/15/1999 - "
KF25706 was also shown to possess antitumor activity against human breast carcinoma MCF-7, colon carcinoma DLD-1, and vulval carcinoma A431 cell lines in vivo in an animal model.
"
3.
Breast Neoplasms (Breast Cancer)
06/15/1999 - "
More importantly, KF25706 showed significant growth-inhibitory activity against human breast carcinoma MX-1 cells transplanted into nude mice at a dose of 100 mg/kg twice daily for five consecutive i.v. injections.
"
06/15/1999 - "
KF25706 was also shown to possess antitumor activity against human breast carcinoma MCF-7, colon carcinoma DLD-1, and vulval carcinoma A431 cell lines in vivo in an animal model.
"
Related Drugs and Biologics
1.
Oximes
2.
monorden (radicicol)
Related Therapies and Procedures
1.
Injections