Sparteine

A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.

Also Known As:

D-sparteine; Depasan Retard; Genisteine Alkaloid; L-Sparteine; Pachycarpine Sulfate (1:1), Pentahydrate, (7S- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine Hydrochloride, (7R- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine Hydrochloride, (7S- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine Hydroiodide, (7R- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine Monohydrochloride, (7R- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine Monohydroiodide, (7R- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine Sulfate; Sparteine Sulfate (1:1), (7S- (7alpha,7aalpha,14alpha,14aalpha))- Isomer; Sparteine Sulfate (1:1), (7S- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine Sulfate Anhydrous; Sparteine, (+)-Isomer; Sparteine, (-)-Isomer; Sparteine, (7R- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine, (7R- (7alpha,7abeta,14alpha,14abeta))- Isomer; Sparteine, (7S- (7alpha,7aalpha,14alpha,14aalpha))- Isomer; Sparteine, (7S- (7alpha,7aalpha,14alpha,14abeta))- Isomer; Sparteine, (7S- (7alpha,7abeta,14alpha,14abeta))- Isomer; alpha-Isosparteine; beta-Isosparteine; Anhydrous, Sparteine Sulfate; Sulfate Anhydrous, Sparteine; alpha Isosparteine; beta Isosparteine; 7,14- Methano- 2H,6H- dipyrido(1,2- a:1',2'- e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-; Lupinidin; Lupinidine; Pachycarpine

Pharmalogical Action Categories:

Anti-Arrhythmia Agents
Oxytocics

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Quinolizidine Alkaloids: 54
    - Sparteine: 87

5,6-dehydrolupanine

Bio-Agent Context: Research Results