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netrin-3

a homolog of NTN2L expressed in sensory ganglia with differential binding to netrin receptors; amino acid sequence in first source

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Breusa, Silvia: 1 article (01/2021)
2.	Combaret, Valérie: 1 article (01/2021)
3.	Delcros, Jean-Guy: 1 article (01/2021)
4.	Ducarouge, Benjamin: 1 article (01/2021)
5.	Gadot, Nicolas: 1 article (01/2021)
6.	Gattolliat, Charles-Henry: 1 article (01/2021)
7.	Gibert, Benjamin: 1 article (01/2021)
8.	Goldshneider, David: 1 article (01/2021)
9.	Hervieu, Maëva: 1 article (01/2021)
10.	Hofman, Paul: 1 article (01/2021)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 05/01/1999 - "Netrin-3 binds with a significantly lower affinity to the netrin receptor DCC (deleted in colorectal cancer) and is also ineffective in eliciting the outgrowth of commissural axons in vitro. " 06/15/1999 - "The murine netrin-3 protein binds to netrin receptors of the DCC (deleted in colorectal cancer) family [DCC and neogenin] and the UNC5 family (UNC5H1, UNC5H2 and UNC5H3). "
2.	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/01/2021 - "Here, we unveiled that netrin-3 appears to be expressed specifically in human neuroblastoma (NB) and small cell lung cancer (SCLC), two subtypes of neuroectodermal/neuroendocrine lineages. " 01/01/2021 - "Targeting netrin-3 in small cell lung cancer and neuroblastoma."
3.	Neuroblastoma 01/01/2021 - "Here, we unveiled that netrin-3 appears to be expressed specifically in human neuroblastoma (NB) and small cell lung cancer (SCLC), two subtypes of neuroectodermal/neuroendocrine lineages. " 01/01/2021 - "Targeting netrin-3 in small cell lung cancer and neuroblastoma."
4.	Neuralgia (Stump Neuralgia) 05/01/2023 - "Netrin-3 Suppresses Diabetic Neuropathic Pain by Gating the Intra-epidermal Sprouting of Sensory Axons."
5.	Neoplasms (Cancer) 01/01/2021 - "Mechanistically, we confirmed the high affinity of netrin-3 for netrin-1 receptors and we demonstrated that netrin-3 genetic silencing or interference using NP137, delayed tumor engraftment, and reduced tumor growth in animal models. " 01/01/2021 - "Interestingly, the epitope recognized by NP137 in netrin-1 shares 90% homology with its counterpart in netrin-3, the closest member to netrin-1 in humans, for which little is known in the field of cancer. "

Related Drugs and Biologics

1.	Netrin Receptors
2.	Proteins (Proteins, Gene)
3.	Netrin-1
4.	neogenin
5.	Epitopes