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N-succinyl-chitosan

Also Known As:

N-succinyl chitosan; N-succinylchitosan; NSC75 compound; NSC88 compound

Networked: 20 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Chitin: 898
      - Chitosan: 6494
        N-succinyl-chitosan: 20
Carbohydrates: 22023
- Polysaccharides: 15383
  - Chitin: 898
    - Chitosan: 6494
      - N-succinyl-chitosan: 20

Experts

1.	Gu, Jiwei: 3 articles (01/2017 - 09/2006)
2.	Liu, Yang: 3 articles (01/2017 - 01/2014)
3.	Yan, Chengyun: 3 articles (01/2017 - 09/2006)
4.	Yuan, Zhi-Qiang: 3 articles (01/2017 - 01/2014)
5.	Chen, Wei-Liang: 2 articles (01/2017 - 01/2017)
6.	Li, Fang: 2 articles (01/2017 - 01/2017)
7.	Yang, Shu-di: 2 articles (01/2017 - 01/2014)
8.	Zhang, Xue-Nong: 2 articles (01/2017 - 01/2017)
9.	Zhu, Qiao-Ling: 2 articles (01/2017 - 01/2017)
10.	Zhu, Wen-Jing: 2 articles (01/2017 - 01/2017)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2002 - "Efficacy of lactosaminated and intact N-succinylchitosan-mitomycin C conjugates against M5076 liver metastatic cancer." 01/01/2015 - "The purpose of this research was to prepare a novel type of Tat tagged and folate modified N-succinyl-chitosan (Tat-Suc-FA) self-assembly nanoparticles, to provide a new vector for tumor gene therapy. " 06/01/2010 - "In vivo biodistribution for tumor targeting of 5-fluorouracil (5-FU) loaded N-succinyl-chitosan (Suc-Chi) nanoparticles." 02/01/1999 - "Biodisposition characteristics of N-succinyl-chitosan and glycol-chitosan in normal and tumor-bearing mice." 09/01/2006 - "Nanoparticles of 5-fluorouracil (5-FU) loaded N-succinyl-chitosan (Suc-Chi) for cancer chemotherapy: preparation, characterization--in-vitro drug release and anti-tumour activity."
2.	Neoplasm Metastasis (Metastasis) 04/01/2002 - "In this study,lactosaminated N-succinyl-chitosan (Lac-Suc) was investigated for its liver targeting ability in the early metastatic stage of liver cancer, and subsequently Lac-Suc-mitomycin C conjugate (Lac-Suc-MMC) and highly-succinylated N-succinyl-chitosan (Suc(II))-MMC conjugate (Suc(II)-MMC) were examined for efficacy against the liver metastasis. "
3.	Liver Neoplasms (Liver Cancer) 04/01/2002 - "In this study,lactosaminated N-succinyl-chitosan (Lac-Suc) was investigated for its liver targeting ability in the early metastatic stage of liver cancer, and subsequently Lac-Suc-mitomycin C conjugate (Lac-Suc-MMC) and highly-succinylated N-succinyl-chitosan (Suc(II))-MMC conjugate (Suc(II)-MMC) were examined for efficacy against the liver metastasis. "
4.	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/01/2023 - "Preparation and physicochemical characterization of N-succinyl chitosan-coated liposomes for oral delivery of grape seed extract and evaluation of its effect on pulmonary fibrosis induced by bleomycin in rats." 01/01/2023 - "In rats, oral administration of N-succinyl chitosan-coated liposomes containing grape seed extract at the 400 mg/kg dose ameliorates bleomycin-induced pulmonary fibrosis."
5.	Colitis 09/15/2011 - "N-Succinyl-chitosan systems for 5-aminosalicylic acid colon delivery: in vivo study with TNBS-induced colitis model in rats." 01/10/2017 - "The present study developed novel zinc ion cross-linked alginate/N-succinyl-chitosan (NSC) blend microspheres (MS) for co-delivery of zinc and 5-aminosalicylic acid (5-ASA) for synergistic therapy of colitis. " 01/10/2017 - "Co-delivery of zinc and 5-aminosalicylic acid from alginate/N-succinyl-chitosan blend microspheres for synergistic therapy of colitis."

Related Drugs and Biologics

1.	Mitomycin (Mitomycin-C)
2.	Grape Seed Extract
3.	Liposomes (Liposome)
4.	Bleomycin (Blenoxane)
5.	Mesalamine (Mesalazine)
6.	Paclitaxel (Taxol)
7.	LDL Lipoproteins (beta Lipoproteins)
8.	Small Interfering RNA (siRNA)
9.	Folic Acid (Vitamin M)
10.	Alginates

Related Therapies and Procedures

1.	Oral Administration
2.	Therapeutics
3.	Microspheres (Microsphere)
4.	Drug Therapy (Chemotherapy)