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diphenylhydantoic acid

structure in first source

Also Known As:

DPHA

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Imidazolidines: 39
        Hydantoins: 306
        Phenytoin: 5446
        diphenylhydantoic acid: 4

Experts

1.	Joseph, Lynnette: 2 articles (11/2021 - 01/2021)
2.	Sajan, D: 2 articles (11/2021 - 01/2021)
3.	Ittyachan, Reena: 1 article (11/2021)
4.	Leenaraj, D R: 1 article (11/2021)
5.	Shyni, V: 1 article (11/2021)
6.	D R, Leenaraj: 1 article (01/2021)
7.	V, Shyni: 1 article (01/2021)
8.	Li, Zhimin: 1 article (01/2012)
9.	Lou, Linjie: 1 article (01/2012)
10.	Zhou, Wenjun: 1 article (01/2012)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 11/01/2021 - "The results of the structure-activity studies and bioactivity studies signify that the DPHA molecule is more active than the DPH molecule against lung cancer." 01/01/2021 - "The in vitro cytotoxic effects of DPH and DPHA molecules on lung cancer cell lines were analyzed using the MTT assay and the SERS method."
2.	Chromosome Aberrations (Chromosome Abnormalities) 02/01/1999 - "In preclinical safety studies, DPHA was without effect in the Ames assay and at concentrations up to 3000 microg/plate in the presence or absence of metabolic activation, and in the in vitro micronucleus test with acute and 2-week repeated dose studies in Wistar rats at iv doses up to 15 mg/kg. In 4-week studies conducted in rats and dogs receiving fosphenytoin containing DPHA levels up to 1.1%, and in an in vitro structural chromosome aberration test with DPHA levels up to 2.0%, all findings were consistent with known effects of phenytoin (such as CNS signs and increased liver weight), and none were attributed to DPHA. "
3.	Neoplasms (Cancer) 01/01/2012 - "The formation of phenazine from diphenylamine (DPhA) chloramination was studied and its cytotoxicities for two human cancer cells were also investigated. "

Related Drugs and Biologics

1.	Phenytoin (Dilantin)
2.	fosphenytoin (Cerebyx)
3.	Diphenylamine
4.	phenazine