angiopoietin 4

Mouse RefSeq NM_009641, Human RefSeq NM_015985

Also Known As:

ANGPT4 protein, human; Angpt4 protein, mouse; Angpt4 protein, rat; Angpt4 protein, zebrafish; angiopoietin 4 protein, mouse; angiopoietin 4 protein, rat; angiopoietin 4 protein, zebrafish; angiopoietin-4

Networked: 12 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Angiogenic Proteins: 403
      - Angiopoietins: 1033
        angiopoietin 4: 12
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Angiogenic Proteins: 403
      - Angiopoietins: 1033
        angiopoietin 4: 12
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Angiogenic Proteins: 403
    - Angiopoietins: 1033
      - angiopoietin 4: 12

Experts

1.	Belanger, Adam J: 2 articles (10/2004 - 10/2003)
2.	Cheng, Seng H: 2 articles (10/2004 - 10/2003)
3.	Date, Taro: 2 articles (10/2004 - 10/2003)
4.	Gregory, Richard J: 2 articles (10/2004 - 10/2003)
5.	Jiang, Canwen: 2 articles (10/2004 - 10/2003)
6.	Kuriyama, Takayuki: 2 articles (10/2004 - 10/2003)
7.	Liu, Louis X: 2 articles (10/2004 - 10/2003)
8.	Yamakawa, Midori: 2 articles (10/2004 - 10/2003)
9.	Fan, Chenghong: 1 article (12/2021)
10.	Huang, Jinlong: 1 article (12/2021)

Related Diseases

1.	Hypoxia (Hypoxemia) 10/01/2004 - "In RPTE cells, angiopoietin-4 (Ang-4) expression was selectively induced by hypoxia or by expression of a hybrid form of HIF-1alpha. " 12/01/2013 - "ANDV infection in combination with hypoxic conditions resulted in the enhancement of hypoxia-inducible factor 1α (HIF1α)-directed VEGF A, angiopoietin 4, and EGLN3 transcriptional responses. " 03/01/2004 - "Irradiation at any dose did not affect the cellular protein levels of any of the angiopoietins, whereas hypoxia led to increasing levels of both angiopoietin-4 and angiopoietin-2. " 01/01/2016 - "MSCs were treated with various concentrations of ET-1 and the expression of cyclooxygenase-2 (COX-2), hypoxia-inducible factor-1 (HIF-1), C-X-C chemokine receptor type 4 (CXCR4), C-C chemokine receptor type 2 (CCR2), vascular endothelial growth factor (VEGF), angiopoietin-2 (Ang-2), angiopoietin-4 (Ang-4) and matrix metalloproteinase-2 (MMP-2) were examined. " 10/03/2003 - "In primary human endothelial cells, hypoxia, desferrioxamine, or infection with Ad2/HIF-1alpha/VP16, an adenoviral vector encoding a constitutively stable hybrid form of HIF-1alpha, increased the mRNA and protein levels of VEGF, angiopoietin-2 (Ang-2), and angiopoietin-4 (Ang-4). "
2.	Neoplasms (Cancer) 09/15/2010 - "Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis." 12/01/2013 - "Six of the 15 angiogenesis factors were upregulated in dormant cancer cells (tissue inhibitor of metalloproteinases-3, TIMP3; thrombospondin-1, TSP1; angiopoietin-1; angiopoietin-2; angiopoietin-4; E-cadherin, CDH1). "
3.	Infections 12/01/2013 - "ANDV infection in combination with hypoxic conditions resulted in the enhancement of hypoxia-inducible factor 1α (HIF1α)-directed VEGF A, angiopoietin 4, and EGLN3 transcriptional responses. " 10/03/2003 - "In primary human endothelial cells, hypoxia, desferrioxamine, or infection with Ad2/HIF-1alpha/VP16, an adenoviral vector encoding a constitutively stable hybrid form of HIF-1alpha, increased the mRNA and protein levels of VEGF, angiopoietin-2 (Ang-2), and angiopoietin-4 (Ang-4). "
4.	Teratocarcinoma 09/01/2008 - "Candidate regulatory growth factor proteins mediating both paracrine and autocrine cell-cell interactions include macrophage inflammatory protein (MIP1 beta), teratocarcinoma-derived growth factor 1 (TDGF1), stromal derived growth factor 1 (SDF1; i.e., CXCL12), growth differentiation factor 8 (GDF8), glia maturation factor gamma (GMFG), osteopontin (SPP1), angiopoietin 4 (ANGPT4), and chemokine ligands (CCL 2, 3, 5, and 8). "
5.	Wounds and Injuries (Trauma) 12/01/2021 - "VAP-PLGA intensified the effect of ADSCs on up-regulating the levels of p-PI3K/PI3K, p-Akt/Akt, HIF-1α, vascular endothelial growth factor (VEGF), stromal cell-derived factor-1 (SDF-1), C-X-C motif chemokine receptor 4 (CXCR4), angiopoietin-4 (Ang-4), VEGF receptor (VEGFR), and transforming growth factor-β1 (TGF-β1), and down-regulating the levels of interleukin-1 β (IL-1β), IL-18 and IL-6 in wound tissues in chronic skin ulcers in vivo. "

Related Drugs and Biologics

1.	Angiopoietin-2
2.	Angiopoietin-1
3.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
4.	Proteins (Proteins, Gene)
5.	Angiopoietins
6.	Myostatin
7.	Osteopontin
8.	Cyclooxygenase 2 (Cyclooxygenase-2)
9.	TIE Receptors (TIE Receptor Tyrosine Kinases)
10.	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)