TP 3654

aminobutyric acid as a spacer and extended the molecule to include Gly-Gly-Ala-Gly this analog is referred to as TP3654; amino acid sequence in first source

Also Known As:

TP3654; VIP-Aba-Gly-Gly-(D)-Ala-Gly; VIP-aminobutyric acid-glycyl-glycyl-(D)-alanyl-glycine; vasoactive intestinal peptide-Aba-Gly-Gly-Ala-Gly

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Diggles, L: 2 articles (05/2001 - 01/2000)
2.	Marcus, C S: 2 articles (05/2001 - 01/2000)
3.	Minami, C: 2 articles (05/2001 - 01/2000)
4.	Pallela, V: 2 articles (05/2001 - 01/2000)
5.	Pham, H L: 2 articles (05/2001 - 01/2000)
6.	Thakur, M L: 2 articles (05/2001 - 01/2000)
7.	Li, H: 1 article (05/2001)
8.	Patti, R: 1 article (05/2001)
9.	Rao, P S: 1 article (05/2001)
10.	Reddy, K: 1 article (05/2001)

Related Diseases

1.	Neoplasms (Cancer) 02/01/1999 - "The results of all in vitro examinations indicated that the biological activity of TP3654 was equivalent to that of native VIP28 and tumor binding was receptor specific." 01/01/2000 - "The modified peptide, TP 3654, was labeled with Tc-99m and evaluated in normal volunteers, as well as in patients with a history of cancer. "
2.	Colorectal Neoplasms (Colorectal Cancer) 05/01/2001 - "We have prepared a VIP analog (TP3654), labeled it with (99m)Tc, and evaluated it in experimental animals as an agent for imaging colorectal cancer. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)