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NSC 284682

Also Known As:

3'-hydroxydaunorubicin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.

Neoplasms (Cancer)

02/03/1999 - "Among the inhibitors of the enzyme topoisomerase II (an important target for chemotherapeutic drugs) tested in the National Cancer Institute's In Vitro Antineoplastic Drug Screen, NSC 284682 (3'-hydroxydaunorubicin) and NSC 659687 [9-hydroxy-5,6-dimethyl-1-(N-[2(dimethylamino)ethyl]carbamoyl)-6H-pyrido -(4,3-b)carbazole] were the only compounds that were more cytotoxic to tumor cells harboring an activated ras oncogene than to tumor cells bearing wild-type ras alleles. "

Related Drugs and Biologics

1.	Enzymes
2.	Type II DNA Topoisomerases (Topoisomerase II)
3.	Antineoplastic Agents (Antineoplastics)
4.	NSC 659687
5.	carbazole