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8-isoprostaglandin A2

a cyclopentenone isoprostane

Also Known As:

15-A(2t)-IsoP; 15-A(2t)-isoprostane; 8-iso-prostaglandin A2

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins A: 1719
        8-isoprostaglandin A2: 1
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins A: 1719
        8-isoprostaglandin A2: 1

Experts

1.	McLaughlin, BethAnn: 1 article (11/2009)
2.	Milne, Ginger J: 1 article (11/2009)
3.	Morrow, Jason D: 1 article (11/2009)
4.	Musiek, Erik S: 1 article (11/2009)
5.	Vidari, Giovanni: 1 article (11/2009)
6.	Zanoni, Giuseppe: 1 article (11/2009)
7.	Zeiger, Stephanie L H: 1 article (11/2009)

Related Diseases

1.	Stroke (Strokes) 11/15/2009 - "In this work, we demonstrate that 15-A(2t)-IsoP is abundantly produced in stroke-infarcted human cortical tissue. " 11/15/2009 - "These data are the first documentation of significant 15-A(2t)-IsoP formation after acute ischemic stroke and suggest that the addition of 15-A(2t)-IsoP to in vitro models of ischemia may help to more fully recapitulate stroke injury."
2.	Ischemia 11/15/2009 - "These data are the first documentation of significant 15-A(2t)-IsoP formation after acute ischemic stroke and suggest that the addition of 15-A(2t)-IsoP to in vitro models of ischemia may help to more fully recapitulate stroke injury." 11/15/2009 - "Taken with our previous work, these data support a model in which ischemia causes generation of reactive oxygen species, calcium influx, lipid peroxidation, and 15-A(2t)-IsoP formation. "
3.	Ischemic Stroke 11/15/2009 - "These data are the first documentation of significant 15-A(2t)-IsoP formation after acute ischemic stroke and suggest that the addition of 15-A(2t)-IsoP to in vitro models of ischemia may help to more fully recapitulate stroke injury."

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	Calcium