AT 760

structure in first source

Also Known As:

AT-760; dimethyl 6,6'-(3,3'-(1,4-phenylene)diacryloyl)bis(4-chloromethyl-8-hydroxy-2-trifluoromethyl-1,4,5,6-tetrahydropyrrolo(3,2-e)indole-3-carboxylate)

Networked: 22 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        AT 760: 22
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - AT 760: 22

Experts

1.	Bloch, Konrad E: 3 articles (01/2020 - 01/2019)
2.	Furian, Michael: 3 articles (01/2020 - 01/2019)
3.	Mademilov, Maamed: 3 articles (01/2020 - 01/2019)
4.	Ulrich, Silvia: 3 articles (01/2020 - 01/2019)
5.	Aeschbacher, Sayaka S: 2 articles (01/2020 - 01/2019)
6.	Bisang, Maya: 2 articles (01/2020 - 01/2019)
7.	Lichtblau, Mona: 2 articles (01/2020 - 01/2019)
8.	Marazhapov, Nuriddin H: 2 articles (01/2020 - 01/2019)
9.	Sheraliev, Ulan: 2 articles (01/2020 - 01/2019)
10.	Sooronbaev, Talant M: 2 articles (01/2020 - 01/2019)

Related Diseases

1.	Chronic Obstructive Pulmonary Disease (COPD) 01/01/2020 - "In healthy individuals and patients with chronic obstructive pulmonary disease participating in clinical field studies at different altitudes, arterial blood samples were obtained at rest and during exercise in a hospital at 760 m and in a high altitude clinic at 3100 m. " 01/01/2020 - "In a large cohort of patients with moderate COPD, our randomized trial showed that the prevalence of RLS increased from 48% at 760 m to 75% at 3,100 m in patients taking placebo. " 01/01/2019 - "A randomized, placebo-controlled, double-blind, parallel trial was performed from May 1 to August 31, 2015, in 118 patients with COPD (forced expiratory volume in the first second of expiration [FEV1] >50% predicted, pulse oximetry at 760 m ≥92%) who were living at altitudes below 800 m. "
2.	Neoplasms (Cancer) 09/07/2016 - "Moreover, brief two-photon irradiation (3 scans of 1.57 s) at 760 nm at high laser power (3 W) was shown to induce 40% of cancer cell death demonstrating the potential of the dual-functionalized mesoporous organosilica nanoparticles for two-photon photodynamic therapy." 04/01/2007 - "The TPL intensity from gold-nanorod-labeled cancer cells is 3 orders of magnitude brighter than the two-photon autofluorescence (TPAF) emission intensity from unlabeled cancer cells at 760 nm excitation light. " 01/01/1997 - "beta-Carotene radical-trapping and autooxidation reactions were faster at 760 mm Hg pO2 than at 150 mm Hg pO2 in both normal and tumor thymocytes and the carotenoid was more rapidly consumed in tumor cells. " 01/01/1997 - "At 760 mm Hg p02, beta-carotene lost its antioxidant activity in normal thymocytes and exhibited a dose-dependent prooxidant effect in tumor thymocytes. "
3.	Hematoma 09/01/1995 - "The difference in absorbance of light (delta OD) at 760 nm between the normal and the hematoma side was measured serially during the first 3 days after injury. " 08/01/1995 - "The difference in absorbance of light (deltaOD) at 760 nm between the normal and the hematoma side was measured serially during the first 3 days after injury. " 07/01/1993 - "In 40 patients intracranial hematomas (22 subdural, 10 epidural, eight intracerebral) were identified on computerized tomography (CT); in all 40 cases, NIRS demonstrated greater absorption of light at 760 nm on the side of the hematoma. "
4.	Hypoxia (Hypoxemia) 06/01/2008 - "Rats lived and trained in normoxia at 760 mmHg (N and NT) or hypobaric hypoxia at 550 mmHg (approximately 2,800 m) (H and HT). " 03/01/1989 - "To examine the effect of hypobaric hypoxia on plasma lipid profiles, fasting blood samples were collected from six men (21-31 yr) at 760 Torr and periodically during a 40-day exposure to decreasing barometric pressure culminating in a final ambient pressure of 282 Torr. " 01/01/1978 - "When used in a dose of 100 mg/kg gutimine alpha-ketogluterate exerts a pronounced antihypoxic action in hypo- and normabaric hpoxic hypoxia ("lifting" albino mice in a pressure chamber to an "altitude" of 10000 m, rarefaction down to 198.7 mm of Hg, PO2--42 mm Hg, the chamber atmosphere containing 5.4 vol % of oxygen with the animals placed in the hermetically sealed chamber containing 5% of oxygen and 95% of nitrogen at 760 mm Hg). "
5.	Phototoxic Dermatitis (Phototoxicity) 09/24/2019 - "These PHT-PMO nanoparticles had no dark toxicity but high phototoxicity when irradiated at 650 nm, and remarkable near-infrared phototoxicity when excited at 760 and 810 nm. The PHT-PMO were then aminated to promote electrostatic complexation with siRNA. "

Related Drugs and Biologics

1.	Oxygen (Dioxygen)
2.	Small Interfering RNA (siRNA)
3.	beta Carotene (Betacarotene)
4.	Steam
5.	Viral RNA
6.	Nitrogen
7.	Lipids
8.	Immunoglobulin G (IgG)
9.	Guanylthiourea
10.	Gold

Related Therapies and Procedures

1.	Lasers (Laser)
2.	Photochemotherapy (Photodynamic Therapy)