attachment protein G

an envelope glycoprotein from members of the Pneumovirus genus as well as from Hendra virus; it is responsible for binding the virus to specific receptor molecules on the host cell surface and is similar to HN PROTEIN; GenBank AF017149

Also Known As:

Networked: 12 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Coyle, Elizabeth M: 2 articles (01/2018 - 01/2016)
2.	Golding, Hana: 2 articles (01/2018 - 01/2016)
3.	Khurana, Surender: 2 articles (01/2018 - 01/2016)
4.	Klenow, Laura: 1 article (01/2018)
5.	Lee, Jeehyun: 1 article (01/2018)
6.	Jardetzky, Theodore S: 1 article (10/2017)
7.	Komives, Elizabeth A: 1 article (10/2017)
8.	Lamb, Robert A: 1 article (10/2017)
9.	Leser, George P: 1 article (10/2017)
10.	Liu, Shiheng: 1 article (10/2017)

Related Diseases

1.	Respiratory Syncytial Virus Infections 01/01/2018 - "Whole genome-fragment phage display libraries (GFPDL) expressing linear and conformational epitopes from RSV bound 100-fold more phages within attachment protein (G) following primary RSV infection. " 04/01/2003 - "Respiratory syncytial virus (RSV) fusion protein subunit F2, not attachment protein G, determines the specificity of RSV infection." 06/21/1996 - "Type-specific serologic diagnosis of respiratory syncytial virus infection, based on a synthetic peptide of the attachment protein G." 01/01/2016 - "Whole genome-fragment phage display libraries (GFPDL) expressing linear and conformational epitopes in the RSV fusion protein (F) and attachment protein (G) were used for unbiased epitope profiling of infant sera prior to and following RSV infection. "
2.	Infections 04/01/2003 - "Thus, the role of the nominal attachment protein G is confined to facilitating infection in a non-species-specific manner, most probably by binding to cell surface glycosaminoglycans. " 08/01/1999 - "Infection is mediated, in part, by an initial interaction between attachment protein (G) and a highly sulfated heparin-like glycosaminoglycan (Gag) located on the cell surface. " 10/03/2017 - "Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F) protein, which carries out the process of virus-cell membrane fusion. " 10/01/2003 - "There is currently no effective antiviral treatment for the infection, but advances in our understanding of RSV uptake, especially the role of surfactant proteins, the attachment protein G and the fusion protein F, as well as the post-binding events, have revealed potential targets for new therapies and vaccine development. "
3.	Eosinophilia 10/15/2002 - "In BALB/c mice, sensitization with the attachment protein (G) of respiratory syncytial virus (RSV) leads to CD4(+) T cell-mediated lung eosinophilia during subsequent challenge with RSV. " 12/01/1998 - "In BALB/c mice, sensitization with the attachment protein (G) of respiratory syncytial virus (RSV) leads to CD4+ T cell-mediated lung eosinophilia during subsequent challenge with RSV. " 12/15/2000 - "In mice, IL-12 treatment down-regulates type 2 cytokine responses to the attachment protein G of RSV, reducing lung eosinophilia but further enhancing illness. "
4.	Vesicular Stomatitis 12/01/2002 - "In this paper, we have tested the ability of the RSV attachment protein, G, to complement virus attachment of a recombinant vesicular stomatitis virus (VSVdeltaG*), which lacks any viral attachment protein. " 12/13/2013 - "Four groups of ferrets received a single vaccination with different recombinant vesicular stomatitis virus vectors expressing: Group 1, control with no glycoprotein; Group 2, the NiV fusion protein (F); Group 3, the NiV attachment protein (G); and Group 4, a combination of the NiV F and G proteins. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Glycosaminoglycans
3.	Glycoproteins (Glycoprotein)
4.	Epitopes
5.	Protein Subunits (Protein Subunit)
6.	GTP-Binding Proteins (G-Protein)
7.	Interleukin-12 (IL 12)
8.	Cytokines
9.	Vaccines
10.	Surface-Active Agents (Surfactants)

Related Therapies and Procedures

1.	Therapeutics