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mesotocin receptor

expressed in prostate gland of the tammar wallaby Macropus eugenii; amino acid sequence in first source

Also Known As:

MT receptor; mesotocin receptors; receptor, mesotocin

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Peptide Receptors: 1159
        Pituitary Hormone Receptors
        mesotocin receptor: 3

Experts

1.	Millan, Mark J: 1 article (01/2022)
2.	Chen, Hui: 1 article (04/2020)
3.	Chen, Yi-Fan: 1 article (04/2020)
4.	Hao, Er-Ying: 1 article (04/2020)
5.	Huang, Chen-Xuan: 1 article (04/2020)
6.	Huang, Ren-Lu: 1 article (04/2020)
7.	Tong, Ya-Guang: 1 article (04/2020)
8.	Wang, De-He: 1 article (04/2020)
9.	Zhou, Rong-Yan: 1 article (04/2020)
10.	Fichna, Jakub: 1 article (05/2016)

Related Diseases

1.	Colitis 05/01/2016 - "Our data suggests that melatonin attenuates colitis by additional, MT receptor-independent pathways." 05/01/2016 - "Melatonin, but not MT receptor agonists, exerts potent anti-inflammatory action in acute TNBS-induced colitis. " 05/01/2016 - "The aim of the present study was to characterize the role of melatonin receptors (MT) in the anti-inflammatory effect of melatonin and to assess the anti-inflammatory potential of two novel MT receptor agonists, Neu-P11 and Neu-P67, in the mouse model of trinitrobenzenesulfonic acid (TNBS)-induced colitis. "
2.	Anxiety Disorders (Anxiety Disorder) 01/01/2022 - "• The study showed that agomelatine 'blocks' a receptor in nerve cells, which plays a role in causing anxiety, called the 5-HT2C receptor.• Blocking this receptor, especially in specific brain regions such as nerve cells of the amygdala, bed nucleus of stria terminalis, and hippocampus, produced the anxiety reduction seen during agomelatine treatment.• Agomelatine also activates the melatonin (MT) receptor, which is known to keep anxiety in check, promote sleep, and maintain the sleep cycle.• Agomelatine should thus tackle sleep disturbances commonly seen in patients with GAD.• Beyond 5-HT2C and MT receptors, signalling molecules in nerve cells that are known to be involved in anxiety disorders (called 'neurotransmitters' and 'neuropeptides') are also affected by agomelatine. "
3.	Ulcer 05/01/2016 - "Luzindole, a MT receptor antagonist, did not inhibit the anti-inflammatory effect of melatonin (macroscopic score 1.12 ± 0.22, ulcer score 0.50 ± 0.16); however, luzindole increased MPO activity (7.57 ± 1.05). "
4.	Tuberous Sclerosis (Bourneville's Disease) 04/01/2020 - "There were higher expression levels in MT receptor A (P < 0.05), melatonin receptor B (P < 0.01), and tuberous sclerosis complex 2 (P < 0.01). "
5.	Inflammation (Inflammations) 05/01/2016 - "MT receptor agonists Neu-P11 and Neu-P67 did not improve inflammation induced by TNBS. "

Related Drugs and Biologics

1.	Melatonin
2.	Melatonin Receptors (Melatonin Receptor)
3.	5-HT2C Serotonin Receptor
4.	Neurotransmitter Agents (Neurotransmitter)
5.	Trinitrobenzenesulfonic Acid
6.	Neuropeptides
7.	N- (2- (5- methoxy- indol- 3- yl)- ethyl)- 4- oxo- 4H- pyran- 2- carboxamide
8.	agomelatine (S20098)
9.	luzindole