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oxysterol 7-alpha-hydroxylase

a widely distributed P-450 enzyme found in brain, testis, ovary, prostate, liver, colon, kidney, and small intestine; catalyzes 7-alpha-hydroxylation of a broad spectrum of substrates including dehydroepiandrosterone, pregnenolone, 25- or 27-hydroxycholesterol; is important in bile acid synthesis; mutation of CYP7B1 gene causes severe neonatal giant cell HEPATITIS
Also Known As:
25-HC 7alpha-hydroxylase; 25-hydroxycholesterol 7-alpha-hydroxylase; 25-hydroxycholesterol 7alpha-hydroxylase; 3 beta-hydroxysteroid 7-alpha-hydroxylase; 3 beta-hydroxysteroid-7 alpha-hydroxylase; 5 alpha-androstane 3 beta,17 beta-diol 7 alpha-hydroxylase; 5alpha-androstane-3beta,17beta-diol 7-alpha-hydroxylase; DHEA 7-alpha-hydroxylase; dehydroepiandrosterone 7-alpha-hydroxylase; dehydroepiandrosterone 7-hydroxylase; oxysterol 7 alpha-hydroxylase
Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Fortner, Renée T: 1 article (01/2020)
2. Herpel, Ester: 1 article (01/2020)
3. Johnson, Theron S: 1 article (01/2020)
4. Kaaks, Rudolf: 1 article (01/2020)
5. Kühn, Tilman: 1 article (01/2020)
6. Le Cornet, Charlotte: 1 article (01/2020)
7. Sookthai, Disorn: 1 article (01/2020)
8. Walter, Britta: 1 article (01/2020)
9. Björkhem, Ingemar: 1 article (04/2010)
10. Deng, Han-Xiang: 1 article (04/2010)

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4. Alzheimer Disease (Alzheimer's Disease)

Related Drugs and Biologics

1. Estrogen Receptor beta
2. Cholesterol
3. Liver X Receptors