HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

protein kinase III

calcium-dependent kinase that does not require calmodulin; isolated from the mango Mangifera indica

Also Known As:

PK-III

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        protein kinase III: 4

Experts

1.	Gephart, L A: 1 article (02/2001)
2.	Lerman, S E: 1 article (02/2001)
3.	Pelekis, M: 1 article (02/2001)

Related Diseases

1.	Body Weight (Weight, Body) 02/01/2001 - "The results suggest that: (i) the UF(HH-PK) and UF(HC-PK) are chemical specific; (ii) for the chemicals used in this study there is no significant difference between UF(HH-PK) and UF(HC-PK); (iii) the magnitude of UF(HH-PK) and UF(HC-PK) varies between 0.033 and 2.85 with respect to tissue and blood concentrations; (iv) the body weight, the rate of ventilation, the fraction of cardiac output flowing to the liver, the blood : air partition coefficient, and the hepatic extraction ratio are the only parameters that play a critical role in the variability of tissue and blood doses within species; and (v) the magnitude of the UF(HH-PK) and UF(HC-PK) obtained with the simplified steady-state equations is essentially the same with that obtained with PBPK models. "
2.	Glioma (Gliomas) 12/01/1994 - "Previously, we have shown that CaM-dependent protein kinase III phosphorylates elongation factor 2 (EF-2) in proliferating, C6 glioma cells but not in normal white matter, a tissue rich in nonproliferating glia. "
3.	Breast Neoplasms (Breast Cancer) 01/01/1999 - "In summary, the activity of Ca2+/CaM-dependent protein kinase III is controlled by breast cancer mitogens and appears to be constitutively activated in human breast cancer. "
4.	AIDS-Related Complex (ARC) 10/31/2023 - "Out of these, 29 CGs have high expression in roots and encoded the following proteins having a role in resistance to plant parasitic nematodes (PPNs): (i) NB-ARC,P-loop containing NTP hydrolase, (ii) Protein Kinase, (iii) serine-threonine/tyrosine-PK, (iv) protein with leucine-rich repeat, (v) virus X resistance protein-like, (vi) zinc finger protein, (vii) RING/FYVE/PHD-type, (viii) glycosyl transferase, family 8 (GT8), (ix) rubisco protein with small subunit domain, (x) protein with SANT/Myb domain and (xi) a protein with a homeobox. "

Related Drugs and Biologics

1.	Peptide Elongation Factor 2 (EF-2)
2.	Tyrosine (L-Tyrosine)
3.	Transferases
4.	Threonine (L-Threonine)
5.	Serine (L-Serine)
6.	Ribulose-Bisphosphate Carboxylase (Rubisco)
7.	Proteins (Proteins, Gene)
8.	Mitogens
9.	Leucine (L-Leucine)
10.	Hydrolases