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poly-APS

an alkylpyridinium polymer based on N-butyl-3-butylpyridinium; isolated from the sponge Reniera sarai; structure in first source

Also Known As:

3-alkylpyridinium salt

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - poly-APS: 4
Biomedical and Dental Materials
- Polymers: 13051
  - poly-APS: 4
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - poly-APS: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridinium Compounds: 5
      - poly-APS: 4

Experts

1.	Paleari, Laura: 2 articles (07/2013 - 12/2006)
2.	Turk, Tom: 2 articles (07/2013 - 12/2006)
3.	Filipič, Metka: 1 article (07/2013)
4.	Kem, William R: 1 article (07/2013)
5.	Kološa, Katja: 1 article (07/2013)
6.	Lewensohn, Rolf: 1 article (07/2013)
7.	Viktorsson, Kristina: 1 article (07/2013)
8.	Xing, Hong: 1 article (07/2013)
9.	Zovko, Ana: 1 article (07/2013)
10.	Drevenšek, Gorazd: 1 article (11/2012)

Related Diseases

1.	Cardiotoxicity 11/01/2012 - "In addition, cardiac toxicity was studied by measuring coronary flow, lactate dehydrogenase release rate, left ventricular pressure, heart rate, and the duration of arrhythmias in isolated rat hearts perfused with poly-APS (0.001-1 μM). "
2.	Neoplasms (Cancer) 12/01/2006 - "Exposure of normal lung fibroblast and NSCLC cell lines to poly-APS revealed a selective cytotoxicity for cancer cells as compared to the normal fibroblast cell lines. "
3.	Hemolysis 10/01/1999 - "The influence of different divalent cations and lipids on poly-APS induced hemolysis is discussed. "
4.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/16/2013 - "Naturally occurring 3-alkylpyridinium polymers (poly-APS) from the marine sponge Reniera sarai, consisting of monomers containing polar pyridinium and nonpolar alkyl chain moieties, have been demonstrated to exert a wide range of biological activities, including a selective cytotoxicity against non-small cell lung cancer (NSCLC) cells. "

Related Drugs and Biologics

1.	Polymers
2.	Lipids
3.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)
4.	Divalent Cations