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dimethylaminoethyl chloride
dimethylamine precursor
Also Known As:
2-dimethylaminoethylchloride; DMAEC; N,N-dimethylaminoethyl chloride
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Ethylamines: 5
dimethylaminoethyl chloride: 2
Related Diseases
1.
Body Weight (Weight, Body)
11/01/1998 - "
The oral administration of equimolar amounts (1 mmol/kg body weight) of potential amine precursors to male Wistar rats produced only small increases in urinary dimethylamine after choline (+ 11%; 0.60 +/- 0.36% dose), dimethylaminopropanol (+ 32%; 1.49 +/- 0.30% dose), dimethylaminoethyl chloride (+ 110% 5.38 +/- 1.72% dose) and trimethylamine (+ 51%; 1.6 +/- 0.80% dose) input, whereas significantly larger increases were found following trimethylamine N-oxide ingestion (+ 355%; 12.93 +/- 1.13% dose; t-test, P < 0.001).
"
01/01/1989 - "
Water, choline, dimethylaminoethanol, diethylaminoethanol, phosphocholine, betaine, carnitine, beta-methylcholine or dimethylaminoethyl chloride were administered by orogastric intubation, and the urine was collected for 24 hr. Administration of choline (15 mmol/kg body weight) resulted in increased urinary excretion of dimethylamine, trimethylamine and trimethylamine oxide (increases of approximately twofold, 500-fold and 50-fold, respectively).
"
Related Drugs and Biologics
1.
Choline (Choline Chloride)
2.
dimethylamine (dimethylamine nitrate)
3.
trimethylamine
4.
trimethyloxamine (trimethylamine N-oxide)
5.
Phosphorylcholine (Phosphocholine)
6.
Deanol (Dimethylethanolamine)
7.
Carnitine (L-Carnitine)
8.
Betaine (C.B.B.)
9.
Amines
10.
dimethylaminopropanol
Related Therapies and Procedures
1.
Oral Administration