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5- Bromo- 6- methoxy- 5,6- dihydro- 3'- azidothymidine- 5'- (p- methoxyphenyl)methoxyalaninyl phosphate

structure in first source

Also Known As:

WHI 05; WHI-05

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Thymidine: 4460
        Zidovudine: 3074
        5-Bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl)methoxyalaninyl phosphate: 2
    - Pyrimidine Nucleotides: 48
      - Thymine Nucleotides: 9
        Thymidine Monophosphate: 1411
        5-Bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl)methoxyalaninyl phosphate: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Thymidine: 4460
      - Zidovudine: 3074
        5-Bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl)methoxyalaninyl phosphate: 2
  - Deoxyribonucleosides: 34
    - Thymidine: 4460
      - Zidovudine: 3074
        5-Bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl)methoxyalaninyl phosphate: 2
    - Dideoxynucleosides: 27
      - Zidovudine: 3074
        5-Bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl)methoxyalaninyl phosphate: 2

Experts

1.	D'Cruz, Osmond J: 1 article (01/2003)
2.	Uckun, Fatih M: 1 article (01/2003)

Related Diseases

1.	Inflammation (Inflammations) 05/01/1999 - " Repetitive intravaginal application of a 2% WHI-05 gel-microemulsion did not injure the vaginal epithelium or stimulate local inflammation in the rabbit model. " 05/01/1999 - "Repetitive intravaginal application of a 2% WHI-05 gel-microemulsion did not damage the vaginal epithelium or cause local inflammation in the rabbit model. "
2.	Acquired Immunodeficiency Syndrome (AIDS) 01/01/2003 - "WHI-05 (5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl) methoxyalaninyl phosphate, CAS 213982-93-5) is a highly promising anti-viral and spermicidal agent with clinical potential as a vaginal contraceptive which can prevent the sexual transmission of AIDS. "

Related Drugs and Biologics

1.	Contraceptive Agents (Contraceptives)