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4-phenyl-2-propionamidotetraline

Subscribe to New Research on 4-phenyl-2-propionamidotetraline

melatonin receptor antagonist; structure in first source

Also Known As:

4P-PDOT

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Hydrocarbons: 412
  - Cyclic Hydrocarbons: 3
    - Aromatic Hydrocarbons: 132
      - Aromatic Polycyclic Hydrocarbons: 831
        Naphthalenes: 9
        Tetrahydronaphthalenes: 1
        4-phenyl-2-propionamidotetraline: 4
Polycyclic Compounds: 56
- Aromatic Polycyclic Hydrocarbons: 831
  - Naphthalenes: 9
    - Tetrahydronaphthalenes: 1
      - 4-phenyl-2-propionamidotetraline: 4

Experts

1.	Ding, Ji-Fei: 1 article (01/2015)
2.	Liu, Jin: 1 article (01/2015)
3.	Deng, Yun-Kun: 1 article (01/2015)
4.	Yang, Yong-Yao: 1 article (01/2015)
5.	Chern, Chang-Ming: 1 article (05/2012)
6.	Liao, Jyh-Fei: 1 article (05/2012)
7.	Wang, Yea-Hwey: 1 article (05/2012)
8.	Shen, Yuh-Chiang: 1 article (05/2012)
9.	Tipoe, George L: 1 article (01/2004)
10.	Liong, Emily C: 1 article (01/2004)

Related Diseases

1.	Stroke (Strokes) 05/01/2012 - "RT-PCR revealed that the gene expression levels of doublecortin, ki67, adamts20, and adam11 are markedly reduced by stroke, but are restored by melatonin treatment; furthermore, pretreatment with 4P-PDOT and luzindole antagonized melatonin's restorative effect. "
2.	Pain (Aches) 01/01/2015 - "Heat pain latency in PHN rats were lower than that of control group (P<0.05), MT could increase the heat pain latency with dose-dependent, while naloxone, 4P-PDOT and L-arginine could reverse the analgesic effect of MT (P<0.05). "
3.	Neoplasms (Cancer) 10/01/2003 - "The receptor subtype identity of melatonin receptor expressed in the cancer tissue was determined by comparison of the rank order of inhibition constants (Ki) of various melatonergic ligands and the affinity of 4-phenyl-2-propionamidotetraline relative to melatonin in inhibiting 2-[125I]iodomelatonin binding to the tumor sample and to human cell lines stably transfected with MT1 or MT2 melatonin receptor subtype. "
4.	Acidosis 01/01/2004 - "The melatonin-induced attenuation of the [Ca2+]i response to hypercapnic acidosis was abolished by pretreatment with an non-selective mt1/MT2 antagonist, luzindole, and by MT2 antagonists, 4-phenyl-2-propionamidotetraline or DH97. "

Related Drugs and Biologics

1.	Melatonin
2.	luzindole
3.	MT2 Melatonin Receptor
4.	Melatonin Receptors (Melatonin Receptor)
5.	Naloxone (Narcan)
6.	Ligands
7.	Arginine (L-Arginine)
8.	N-pentanoyl-2-benzyltryptamine (DH97)