5- fluoro- 1- (2'- deoxy- 2'- fluoro- ribofuranosyl)uracil

a substrate for the mammalian thymidine kinase and HSV-tk

Also Known As:

5-fluoro-1-(2'-deoxy-2'-fluoro-beta-D-ribofuranosyl)uracil; FFUdR

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 01/01/1996 - "Of the three analogs tested, only FFUdR showed preferential retention in rapidly proliferating tissues, such as the spleen and implanted tumors, and it attained tissue to blood ratios of 2.1 at 2 h." 08/01/1998 - "The FFUdR uptake is an indicator of the HSV-tk activity in tumor cells and can be used as a prognostic marker during gene therapy with HSV-tk. "

1.	Indicators and Reagents (Reagents)