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2- amino- 3- (3,5- dibromo- 4- (4- hydroxy- 3- (6- oxo- 1,6- dihydro- pyridazin- 3- ylmethyl)- phenoxyl)- phenyl)- propionic acid

a thyromimetic compound

Also Known As:

L-94901

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - 2-amino-3-(3,5-dibromo-4-(4-hydroxy-3-(6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxyl)-phenyl)-propionic acid: 3
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - 2-amino-3-(3,5-dibromo-4-(4-hydroxy-3-(6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxyl)-phenyl)-propionic acid: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 11
    - 2-amino-3-(3,5-dibromo-4-(4-hydroxy-3-(6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxyl)-phenyl)-propionic acid: 3

Experts

1.	Hara, M: 1 article (05/2000)
2.	Hashizume, K: 1 article (05/2000)
3.	Ichikawa, K: 1 article (05/2000)
4.	Kakizawa, T: 1 article (05/2000)
5.	Kaneko, A: 1 article (05/2000)
6.	Kumagai, M: 1 article (05/2000)
7.	Miyamoto, T: 1 article (05/2000)
8.	Mori, J: 1 article (05/2000)
9.	Suzuki, S: 1 article (05/2000)
10.	Takeda, T: 1 article (05/2000)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 05/01/2000 - "The mechanisms of liver-selectivity of SK&F L-94901 were examined using cultured rat hepatoma cells (dRLH-84) and rat pituitary tumor cells (GH3), both of which showed saturable cellular uptake of tri-iodothyronine (T(3)). " 01/13/1992 - "Because receptor binding of L-94901 in isolated heart and liver nuclei is similar but binding in liver nuclei in vivo was 50-fold higher than in cardiac nuclei, we studied its effect on triiodothyronine (T3) transport across the plasma membrane of myoblasts, hepatoma cells and neuroblasts. "
2.	Sarcoma (Soft Tissue Sarcoma) 01/01/1991 - "Thyroid hormone analogue SKF L-94901 accelerates regression of Moloney sarcoma and inhibits periosteal osteogenesis mediated by this tumour."
3.	Pituitary Neoplasms (Pituitary Adenoma) 05/01/2000 - "The mechanisms of liver-selectivity of SK&F L-94901 were examined using cultured rat hepatoma cells (dRLH-84) and rat pituitary tumor cells (GH3), both of which showed saturable cellular uptake of tri-iodothyronine (T(3)). "

Related Drugs and Biologics

1.	Triiodothyronine (Liothyronine)
2.	Thyroid Hormones