haptotaxin

an autocrine motility factor-like tumor-derived factor that stimulates cell migration on extracellular matrix

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 05/01/1998 - "Haptotaxin potentiated adhesion and spreading of tumor cells on these substrata but did not in itself mediate adhesion and spreading of the cells. " 05/01/1998 - "Anti-VLA-5 monoclonal antibodies inhibited haptotaxin-induced migration on fibronectin coated filters but not such migration on filters coated with other ECM molecules showing that tumor cells must interact specifically with ECM components in order to migrate to haptotaxin."
2.	Carcinoma (Carcinomatosis) 05/01/1998 - "A partially purified autocrine motility factor-like substance, termed haptotaxin, was added to the lower compartment of Boyden chambers and the filters were coated on the upper, lower or both sides with different concentrations of the extracellular matrix (ECM) components fibronectin, laminin or collagen type IV. These adhesive proteins coated on the lower surface of the filter promoted the migration (haptotaxis) of lung carcinoma cells. "

1.	Collagen Type IV (Type IV Collagen)
2.	Proteins (Proteins, Gene)
3.	Laminin (Merosin)
4.	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)
5.	Fibronectins (Fibronectin)
6.	Monoclonal Antibodies