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idonic acid (L-idonate)

RN refers to L-idonate

Also Known As:

L-idonate; L-idonic acid

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Sugar Acids: 4
      - idonic acid: 3
  - Acyclic Acids
    - Sugar Acids: 4
      - idonic acid: 3
Carbohydrates: 22023
- Sugar Acids: 4
  - idonic acid: 3

Experts

1.	Huang, H: 1 article (04/2020)
2.	Liu, Y P: 1 article (04/2020)
3.	Wu, X X: 1 article (04/2020)
4.	Zhang, C F: 1 article (04/2020)
5.	Zhang, X S: 1 article (04/2020)

Related Diseases

1.	Mucopolysaccharidosis III (Sanfilippo Syndrome) 12/01/1981 - "1. Sulphamidase activity was assayed by incubation of the radiolabelled disaccharide O-(alpha-2-sulphamino-2-deoxy-D-glucopyranosyl)- (1 leads to 3)-L-[6-3H]idonic acid with homogenates of leucocytes and cultured skin fibroblasts and concentrates of urine derived from normal individuals, patients affected with sulphamidase deficiency disorder [mucopolysaccharidosis type IIIA (MPS IIIA): the Sanfilippo A syndrome], parents of such patients and patients affected with other mucopolysaccharidoses and lysosomal enzyme deficiencies. " 02/01/1989 - "N-Acetylglucosamine-6-sulfatase activity was assayed by incubation of the radiolabeled disaccharide O-(a-N-acetylglucosamine-6-sulfate)-(1----3)-L-[6-3H]-idonic acid (GlcNAc6S-IdOA), with homogenates of leucocytes, cultured fibroblasts, and urine from normal individuals, patients affected with N-acetylglucosamine-6-sulfatase-deficiency (Sanfilippo D syndrome, mucopolysaccharidosis type IIID), and patients affected with other mucopolysaccharidoses and lysosomal storage disorders. "
2.	Mucopolysaccharidoses 12/01/1981 - "1. Sulphamidase activity was assayed by incubation of the radiolabelled disaccharide O-(alpha-2-sulphamino-2-deoxy-D-glucopyranosyl)- (1 leads to 3)-L-[6-3H]idonic acid with homogenates of leucocytes and cultured skin fibroblasts and concentrates of urine derived from normal individuals, patients affected with sulphamidase deficiency disorder [mucopolysaccharidosis type IIIA (MPS IIIA): the Sanfilippo A syndrome], parents of such patients and patients affected with other mucopolysaccharidoses and lysosomal enzyme deficiencies. " 02/01/1989 - "N-Acetylglucosamine-6-sulfatase activity was assayed by incubation of the radiolabeled disaccharide O-(a-N-acetylglucosamine-6-sulfate)-(1----3)-L-[6-3H]-idonic acid (GlcNAc6S-IdOA), with homogenates of leucocytes, cultured fibroblasts, and urine from normal individuals, patients affected with N-acetylglucosamine-6-sulfatase-deficiency (Sanfilippo D syndrome, mucopolysaccharidosis type IIID), and patients affected with other mucopolysaccharidoses and lysosomal storage disorders. "
3.	Dehydration (Water Stress) 04/01/2020 - "Two associated metabolic pathways were identified: L-idonic acid dehydrogenase was found to be involved in the degradation of L-idonic acid through oxidation/decarboxylation in Agrobacterium radiobacter K84, while 2-hydroxy-3-oxopantoate reductase was found to participate in D-glucarate catabolism through dehydration/cleavage in Ralstonia metallidurans CH34."

Related Drugs and Biologics

1.	Disaccharides
2.	Sulfates (Sulfates, Inorganic)
3.	Oxidoreductases (Dehydrogenase)
4.	Enzymes
5.	Acetylglucosamine
6.	N-sulfoglucosamine sulfohydrolase (sulfamidase)
7.	N-acetylglucosamine-6-sulfatase