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tryptophyl-proline

Also Known As:

Trp-Pro

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - tryptophyl-proline: 7
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Imino Acids: 11
      - Proline: 3391
        tryptophyl-proline: 7

Experts

1.	Miller, Edward D: 1 article (01/2017)
2.	Murota, Itsuki: 1 article (03/2014)
3.	Nakamura, Yasushi: 1 article (03/2014)
4.	Park, Eun Young: 1 article (03/2014)
5.	Sato, Kenji: 1 article (03/2014)
6.	Sato, Nobuyuki: 1 article (03/2014)
7.	Taguchi, Satoko: 1 article (03/2014)

Related Diseases

1.	Body Weight (Weight, Body) 03/19/2014 - "Tyr-Leu-Asp-Asn-Tyr and Ser-Pro-Pro-Tyr-Trp-Pro-Tyr lowered the serum uric acid level via intravenous injection at 5 mg/kg of body weight. " 05/01/1998 - "Anticoagulant, fibrinolytic, and fibrin-depolymerization effects were revealed during in vitro study of five proline-containing peptides (Gly-Pro, Trp-Pro, Pro-Gly, Gly-Pro-Gly-Gly, and Pro-Gly-Pro) in the concentration range 10(-9) to 10(-1) mg/ml. Intravenous injection of Trp-Pro and Pro-Gly into white rats at 250 micrograms/kg body weight significantly increased recalcification time and activated partial thromboplastin time of serum coagulation, increased fibrinolytic activity, decreased the level of serum factor XIII/(/)a and fibrinogen, and reduced thrombocyte aggregation. "
2.	Renal Artery Obstruction (Renal Artery Stenosis) 01/01/2017 - "The elevated blood pressure induced by the renal artery stenosis can be prevented by prior treatment with the nonapeptide Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro, which blocks conversion of angiotensin I to angiotensin II. Further, the nonapeptide can restore systemic pressure to normal in the early phase of renovascular hypertension. " 09/22/1972 - "The elevated blood pressure induced by the renal artery stenosis can be prevented by prior treatment with the nonapeptide Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro, which blocks conversion of angiotensin I to angiotensin II. Further, the nonapeptide can restore systemic pressure to normnal in the early phase of renovascular hypertension. " 02/01/1975 - "The hypertension normally induced by renal artery stenosis is prevented by prior treatment with the nonapeptide Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro (SQ 20, 881), which blocks conversion of angiotensin I to angiotensin II. Constant intravenous infusion of the inhibitor over several days of renal artery constriction prevents the development of chronic renovascular hypertension. "
3.	Renovascular Hypertension (Goldblatt Syndrome) 01/01/2017 - "The elevated blood pressure induced by the renal artery stenosis can be prevented by prior treatment with the nonapeptide Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro, which blocks conversion of angiotensin I to angiotensin II. Further, the nonapeptide can restore systemic pressure to normal in the early phase of renovascular hypertension. " 09/22/1972 - "The elevated blood pressure induced by the renal artery stenosis can be prevented by prior treatment with the nonapeptide Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro, which blocks conversion of angiotensin I to angiotensin II. Further, the nonapeptide can restore systemic pressure to normnal in the early phase of renovascular hypertension. " 02/01/1975 - "The hypertension normally induced by renal artery stenosis is prevented by prior treatment with the nonapeptide Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro (SQ 20, 881), which blocks conversion of angiotensin I to angiotensin II. Constant intravenous infusion of the inhibitor over several days of renal artery constriction prevents the development of chronic renovascular hypertension. "
4.	Cognitive Dysfunction 05/11/2023 - "In this work, RLWPF (Arg-Leu-Trp-Pro-Phe) and VLRLF (Val-Leu-Arg-Leu-Phe) were investigated for the effects against D-galactose (D-gal) induced cognitive impairment by modulating the gut microbiota composition. "
5.	Rubella (German Measles) 01/01/1996 - "The glandular secretions of the skin of Litoria rubella specimens collected from five locations on the eastern seaboard of Queensland (Australia) contain the three tryptophyllin peptides Phe Pro Trp Leu (NH2), Phe Pro Trp Pro (NH2) and Phe Pro Phe Pro Trp Leu (NH2). "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Proline (L-Proline)
3.	Fibrinogen (Factor I)
4.	Fibrin
5.	Factor XIII (Coagulation Factor XIII)
6.	Anticoagulants
7.	prolyl-glycyl-proline
8.	prolylglycine
9.	prolyl-glycyl-glycine
10.	glycylproline (Gly-Pro)

Related Therapies and Procedures

1.	Intravenous Injections
2.	Intravenous Infusions