HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

PAPA NONOate

Also Known As:

1-propamine, 3-(2-hydroxy-2-nitroso-1-propylhydrazine); 3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine; PAPA-NONOate

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chlopicki, Stefan: 1 article (10/2018)
2.	Kaczara, Patrycja: 1 article (10/2018)
3.	Motterlini, Roberto: 1 article (10/2018)
4.	Stojak, Marta: 1 article (10/2018)
5.	Harhaji, Ljubica: 1 article (03/2008)
6.	Janjetovic, Kristina: 1 article (03/2008)
7.	Misirkic, Maja: 1 article (03/2008)
8.	Trajkovic, Vladimir: 1 article (03/2008)
9.	Vucicevic, Ljubica: 1 article (03/2008)
10.	Bedioui, Fethi: 1 article (02/2007)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2018 - "We found that CORM-401 and PAPA NONOate alone or in combination markedly decreased transmigration of breast cancer cells across human lung microvascular endothelial cells (hLMVEC), while cancer cell adhesion to the endothelium was diminished only by a combination of the two compounds. " 02/01/2007 - "These two NO donor molecules allowed proving the electrochemical detection of (i) directly injected exogenous NO phosphate buffer solution into the tumor (decomposed DEA-NONOate) and (ii) biomimetically induced endogeneous release of NO in the tumoral tissue, upon injection of PAPA-NONOate into the tumor. "
2.	Glioma (Gliomas) 03/31/2008 - "To explore combined antiglioma effect of nitric oxide (NO) and hyperthermia, the rat C6 and human U251 glioma cells were exposed to NO-releasing agents sodium nitroprusside(SNP), S-nitrosoglutathione or PAPA-NONOate, followed by hyperthermia (1 h, 43 degrees C). "
3.	Breast Neoplasms (Breast Cancer) 10/01/2018 - "We found that CORM-401 and PAPA NONOate alone or in combination markedly decreased transmigration of breast cancer cells across human lung microvascular endothelial cells (hLMVEC), while cancer cell adhesion to the endothelium was diminished only by a combination of the two compounds. " 10/01/2018 - "Intercellular adhesion molecule-1 (ICAM-1), involved in breast cancer cell adhesion to hLMVECs, was downregulated by CORM-401 and PAPA NONOate, when applied alone, while a combination of both compounds did not cause any enhancement of ICAM-1 downregulation. " 10/01/2018 - "Here we examined the effects of a carbon monoxide-releasing molecule (CORM-401) and a nitric oxide donor (PAPA NONOate) given alone or in combination on breast cancer cell adhesion and transmigration across the lung microvascular endothelium. "
4.	Hyperthermia 03/31/2008 - "To explore combined antiglioma effect of nitric oxide (NO) and hyperthermia, the rat C6 and human U251 glioma cells were exposed to NO-releasing agents sodium nitroprusside(SNP), S-nitrosoglutathione or PAPA-NONOate, followed by hyperthermia (1 h, 43 degrees C). "

Related Drugs and Biologics

1.	S-Nitrosoglutathione
2.	Nitric Oxide Donors
3.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
4.	Solutions
5.	Phosphates (Orthophosphate)
6.	Nitroprusside (Sodium Nitroprusside)
7.	Nitric Oxide (Nitrogen Monoxide)
8.	Carbon Monoxide
9.	Buffers
10.	1,1-diethyl-2-hydroxy-2-nitrosohydrazine