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SC 68448

structure in first source

Also Known As:

SC-68448; SC68448; beta-((2-2-(((3-((aminoiminomethyl)amino)-phenyl)carbonyl)amino)acetyl)amino)-3,5-dichlorobenzenepropanoic acid

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylpropionates
      - SC 68448: 1

Related Diseases

1.	Neoplasms (Cancer) 05/01/1998 - "In cell-based studies, SC-68448 inhibited alpha(v)beta3-mediated endothelial cell proliferation in a dose-dependent manner but did not inhibit tumor cell proliferation, suggesting that effects on endothelial cell proliferation were not due to SC-68448-induced cytotoxicity. " 05/01/1998 - "SC-68448 inhibited the growth of the tumors in mice by up to 80% and completely blocked the development of hypercalcemia. " 05/01/1998 - "A xenogeneic severe combined immune deficiency mouse/rat Leydig cell tumor model was developed for testing SC-68448 as an inhibitor of tumor growth in vivo. "
2.	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 05/01/1998 - "A xenogeneic severe combined immune deficiency mouse/rat Leydig cell tumor model was developed for testing SC-68448 as an inhibitor of tumor growth in vivo. "
3.	Corneal Neovascularization 05/01/1998 - "In accord with these results, SC-68448 inhibited angiogenesis in vivo in a basic fibroblast growth factor-induced rat corneal neovascularization model. "
4.	Leydig Cell Tumor 05/01/1998 - "A xenogeneic severe combined immune deficiency mouse/rat Leydig cell tumor model was developed for testing SC-68448 as an inhibitor of tumor growth in vivo. "
5.	Hypercalcemia (Milk Alkali Syndrome) 05/01/1998 - "SC-68448 inhibited the growth of the tumors in mice by up to 80% and completely blocked the development of hypercalcemia. "

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