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MEN 11149
a potent, selective and orally effective tachykinin NK(1) receptor antagonist; structure in first source
Also Known As:
2-(2-naphthyl)-1-N-((1R,2S)-2-N-(1(H)indol-3-ylcarbonyl)aminocyclohexanecarbonyl)-1-(N'-methyl-N'-(4-methylphenylacetyl))diaminoethane; MEN11149
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
MEN 11149: 1
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
MEN 11149: 1
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
MEN 11149: 1
Experts
1.
Bigioni, M
: 1 article (01/2000)
2.
Irrissuto, C
: 1 article (01/2000)
3.
Maggi, C A
: 1 article (01/2000)
4.
Manzini, S
: 1 article (01/2000)
5.
Nardelli, F
: 1 article (01/2000)
6.
Palma, C
: 1 article (01/2000)
Related Diseases
1.
Glioma (Gliomas)
01/01/2000 - "
Although the administration of exogenous SP did not significantly affect the size or development of U373 MG xenograft, a role of SP in supporting glioma progression in vivo was highlighted by the tumour growth inhibition induced by highly specific and selective human tachykinin NK1 receptor antagonists (MEN 11467 and MEN 11149).
"
Related Drugs and Biologics
1.
Tachykinins
2.
MEN 11467