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8-methyl-1,3,8-trichlorodibenzofuran
structure given in first source
Also Known As:
8-MCDF
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzofurans: 26
8-methyl-1,3,8-trichlorodibenzofuran: 1
Related Diseases
1.
Neoplasms (Cancer)
11/25/1997 - "
At doses of 5, 10 or 25 mg/kg/week, both 6-MCDF and 8-MCDF significantly inhibited mammary tumor growth and at the 5 mg/kg/week dose >50% growth inhibition was observed.
"
2.
Body Weight (Weight, Body)
11/25/1997 - "
The antitumorigenic activity of 6-MCDF or 8-MCDF in the mammary was not accompanied by any significant changes in liver/body weight ratios, liver morphology or induction of hepatic CYP1A1-dependent activity which is one of the most sensitive indicators of exposure to AhR agonists.
"