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5- benzylidenehydrazino- 2- methylpyridazin- 3(2H)- one

an interleukin-1 blocker; structure in first source

Also Known As:

CK 124; CK-124

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrazines: 379
  - 5-benzylidenehydrazino-2-methylpyridazin-3(2H)-one: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 11
    - 5-benzylidenehydrazino-2-methylpyridazin-3(2H)-one: 1

Related Diseases

1.	Uveitis 02/01/1998 - "Effective treatment of experimental uveitis with interleukin-1 blockers, CK 123 and CK 124." 02/01/1998 - "In addition to anti-inflammation, CK 123 and CK 124 were also found to inhibit proliferation of fibroblast-like corneal and conjunctival cells, indicating that these compounds could be used not only as anti-uveitis agents but also as useful agents to prolong the functional period of aqueous humor outflow after trabeculectomy. " 02/01/1998 - "CK 123 and CK 124 are new IL-1 blockers which showed potent anti-uveitis actions that are more potent than the classic corticosteroid, prednisolone. "
2.	Inflammation (Inflammations) 02/01/1998 - "In addition to anti-inflammation, CK 123 and CK 124 were also found to inhibit proliferation of fibroblast-like corneal and conjunctival cells, indicating that these compounds could be used not only as anti-uveitis agents but also as useful agents to prolong the functional period of aqueous humor outflow after trabeculectomy. "

Related Drugs and Biologics

1.	Interleukin-1 (Interleukin 1)
2.	4-benzylidenehydrazinocoumarin
3.	Prednisolone (Predate)
4.	Adrenal Cortex Hormones (Corticosteroids)

Related Therapies and Procedures

1.	Trabeculectomy (Trabeculoplasty)