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NPI 2

inhibits class 3 aldehyde dehydrogenase; structure in first source

Also Known As:

(acetyloxy)((4-chlorophenyl)sulfonyl)carbamic acid 1,1-dimethylethyl ester; NPI-2

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Bowman, Simon J: 1 article (10/2016)
2.	Curnow, S John: 1 article (10/2016)
3.	Denniston, Alastair K O: 1 article (10/2016)
4.	Hamburger, John: 1 article (10/2016)
5.	Nightingale, Peter: 1 article (10/2016)
6.	Rauz, Saaeha: 1 article (10/2016)
7.	Southworth, Sue: 1 article (10/2016)
8.	Tomlins, Paul J: 1 article (10/2016)
9.	Turner, Stephen: 1 article (10/2016)
10.	Williams, Geraint P: 1 article (10/2016)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 11/01/2008 - "The relationship approached significance when comparing NPI 2 to NPI 3 (p=0.058) and disease free patients to non-disease free patients (p=0.052) or those who died of breast cancer (p=0.060). "
2.	Cognitive Dysfunction 01/01/2009 - "The regression model (R2 = 0.35, p < 0.001) shows that the best explanatory variables are: 1) neuropsychiatric symptoms (NPI); 2) difficulties in the IADL; 3) time taken by caregiving; 4) demographic variables such as caregiver's age and patient sex; and 5) severity of cognitive impairment. "
3.	T-Cell Lymphoma (Lymphoma, T Cell) 04/01/2014 - "A prognostic score was devised by totaling the number of these 3 predictors: 0 or 1 = score 0; and 2 or 3 = score 1. As for tumor invasion, local invasion beyond the nasal cavity was associated with poor prognosis, and a prognostic score was devised as: tumor restricted to nasal cavity, yes = score 0; no = score 1. A novel prognostic index (NPI) was established based on these scores from 0 to 2. Disease-specific survival rates at 5 years were: 90.0% for NPI = 0; 29.3% for NPI = 1; and 0.0% for NPI = 2. Our NPI is valid for anticipating prognosis of nasal NK/T-cell lymphoma."
4.	Neoplasms (Cancer) 04/01/2014 - "A prognostic score was devised by totaling the number of these 3 predictors: 0 or 1 = score 0; and 2 or 3 = score 1. As for tumor invasion, local invasion beyond the nasal cavity was associated with poor prognosis, and a prognostic score was devised as: tumor restricted to nasal cavity, yes = score 0; no = score 1. A novel prognostic index (NPI) was established based on these scores from 0 to 2. Disease-specific survival rates at 5 years were: 90.0% for NPI = 0; 29.3% for NPI = 1; and 0.0% for NPI = 2. Our NPI is valid for anticipating prognosis of nasal NK/T-cell lymphoma."
5.	Inflammation (Inflammations) 10/01/2016 - "Overall neutrophils were elevated in OcMMP eyes when compared to pSS or HC (109 [18%] neutrophils/impression [NPI]; 2 [0.2%]; 6 [0.8%], respectively [P < 0.0001]) and in OcMMP patients with no visible inflammation when compared with HC (44.3 [7.9%]; 5.8 [0.8%]; P < 0.05). "