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S-nitro-N-acetylpenicillamine

a NO donor

Also Known As:

N-acetyl-3-(nitrosothio)-D-Valine; S-nitro-N-acetylpenicillamine (SNAP)

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfur Amino Acids: 221
    - Penicillamine: 2699
      - S-nitro-N-acetylpenicillamine: 3
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Sulfur Amino Acids: 221
    - Penicillamine: 2699
      - S-nitro-N-acetylpenicillamine: 3

Experts

1.	Chan, J Y: 1 article (06/2001)
2.	Chan, S H: 1 article (06/2001)
3.	Wang, L L: 1 article (06/2001)
4.	Wang, S H: 1 article (06/2001)

Related Diseases

1.	Tachycardia (Tachyarrhythmias) 06/01/2001 - "Whereas low doses of S-nitro-N-acetylpenicillamine (0.25 or 0.5 nmoles) elicited hypertension and tachycardia, high doses of this non-nitrate NO donor (5 nmoles) induced hypotension and bradycardia. "
2.	Infections 04/01/1995 - "Productive VSV infection of NB41A3 cells was significantly inhibited by an organic NO donor, S-nitro-N-acetylpenicillamine (SNAP), while the control compound N-acetylpenicillamine (NAP) had no effect. "
3.	Hypoglycemia (Reactive Hypoglycemia) 02/06/1995 - "In contrast, treatment with precursors of NO in the arginine-to-NO pathway, such as sodium nitroprusside, S-nitro-N-acetylpenicillamine and N-morpholino sydnonimine exacerbated the 15-min hypoxia/hypoglycemia-induced decrease in the CA1 presynaptic potential. "
4.	Hypertension (High Blood Pressure) 06/01/2001 - "Whereas low doses of S-nitro-N-acetylpenicillamine (0.25 or 0.5 nmoles) elicited hypertension and tachycardia, high doses of this non-nitrate NO donor (5 nmoles) induced hypotension and bradycardia. "
5.	Bradycardia 06/01/2001 - "Whereas low doses of S-nitro-N-acetylpenicillamine (0.25 or 0.5 nmoles) elicited hypertension and tachycardia, high doses of this non-nitrate NO donor (5 nmoles) induced hypotension and bradycardia. "

Related Drugs and Biologics

1.	Nitroprusside (Sodium Nitroprusside)
2.	Nitrates
3.	Arginine (L-Arginine)
4.	N-acetylpenicillamine
5.	linsidomine

Related Therapies and Procedures

1.	Controlled Hypotension