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PH-1126

a pheophorbide derivative; structure in first source

Also Known As:

PH 1126 pheophorbide

Networked: 3 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - Tetrapyrroles: 70
        Chlorophyll: 1072
        PH-1126: 3
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Tetrapyrroles: 70
      - Chlorophyll: 1072
        PH-1126: 3
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Tetrapyrroles: 70
    - Chlorophyll: 1072
      - PH-1126: 3

Experts

1.	Fukuda, M: 2 articles (07/2000 - 05/2000)
2.	Ishiguro, K: 2 articles (07/2000 - 05/2000)
3.	Jin, Z H: 2 articles (07/2000 - 05/2000)
4.	Kumakiri, M: 2 articles (07/2000 - 05/2000)
5.	Miyoshi, N: 2 articles (07/2000 - 05/2000)
6.	Tajiri, H: 2 articles (07/2000 - 05/2000)
7.	Takaoka, K: 2 articles (07/2000 - 05/2000)
8.	Udagawa, T: 2 articles (07/2000 - 05/2000)
9.	Ueda, K: 2 articles (07/2000 - 05/2000)
10.	Kawabata, K: 1 article (05/2000)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2000 - "The combination using PH-1126 resulted in 25% of the treated mice being tumor free at 20 days after treatment. " 07/01/2000 - "This study demonstrated the usefulness of the combination of a low dose PH-1126 with 5-ALA for PDT of experimental tumors in vivo." 07/01/2000 - "The results showed that PDT with 5-ALA plus PH-1126 at a low dose (2.5 mg/kg.bw) were well tolerated by both animal models, with resultant synergistically enhanced inhibition of tumor growth and/or survival advantage for the treated animals. " 05/01/2000 - "The combination of PDT and SDT using either PH-1126 or ATX-70 as a sensitizer resulted in significantly improved inhibition of tumor growth (92-98%) (additive effect) as compared to either single treatment (27-77%). "
2.	Atherosclerotic Plaque (Atheroma) 02/01/1996 - "Twenty-four hours later, PH-1126 selectively accumulated in atherosclerotic plaques. " 02/01/1996 - "The aim of this study was to demonstrate acute efficacy of photodynamic therapy on atheromas by using a pheophorbide derivative, PH-1126. " 02/01/1996 - "It may become possible to flatten atheroma in a long-term period after photodynamic therapy using PH-1126 as a potent photosensitizer."

Related Drugs and Biologics

1.	1-phenyl-3,3-dimethyltriazene (PDT)
2.	ATX 70
3.	Photosensitizing Agents (Photosensitizers)

Related Therapies and Procedures

1.	Photochemotherapy (Photodynamic Therapy)
2.	Aftercare (After-Treatment)