DMRT1 protein

DMRT was formerly called DMT; expressed in testis; RefSeq NM_021951 (human); NM_053706 (rat); NM_015826 (mouse)

Also Known As:

DM domain expressed in testis 1 protein, human; DMRT1 protein, human; DMT1 protein, human; Dmrt1 protein, mouse; Dmrt1 protein, rat; doublesex and mab-3 related transcription factor 1; doublesex and mab-3 related transcription factor 1, human; doublesex and mab-3 related transcription factor 1, mouse; doublesex and mab-3 related transcription factor 1, rat

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Transcription Factors: 38804
    - DMRT1 protein: 5

Experts

1.	Dai, Yichen: 1 article (01/2020)
2.	Guo, Meijin: 1 article (01/2020)
3.	Hang, Haifeng: 1 article (01/2020)
4.	Mohsin, Ali: 1 article (01/2020)
5.	Xu, Chenze: 1 article (01/2020)
6.	Zhuang, Yingping: 1 article (01/2020)
7.	Cheng, Liang: 1 article (12/2018)
8.	Michal, Michael: 1 article (12/2018)
9.	Michal, Michal: 1 article (12/2018)
10.	Roth, Lawrence M: 1 article (12/2018)

Related Diseases

1.	Azoospermia 04/01/2014 - "The objective of the study was to investigate the regulation of meiosis-associated and male germ cell-related genes, stimulated by retinoic acid gene 8 (STRA8), synaptonemal complex protein 3 (SYCP3), dosage suppressor of mck1 (DMC1), doublesex and mab-3 related transcription factor 1 (DMRT1) and deleted in azoospermia-like (DAZL) following exogenous administration of retinoic acid (RA) and after the modulation of endogenous RA by a cytochrome P450, family 26, subfamily B, polypeptide 1 inhibitor (CYP26B1-I; R115866) in an in vitro testis model. "
2.	Sex Cord-Gonadal Stromal Tumors (Sex Cord-Stromal Tumor) 12/01/2018 - "In the present study, we investigated protein expression of the transcription factors mammalian doublesex and mab-3 related transcription factor 1 (DMRT1), basic helix-loop-helix transcription factor-like 5 (TCLF5), and octamer-binding transcription factor 4 (OCT4) in normal human spermatogenesis, testicular mixed germ cell-sex cord stromal tumor (MGC-SCST), spermatocytic tumor, and seminoma. "
3.	Seminoma 12/01/2018 - "In the present study, we investigated protein expression of the transcription factors mammalian doublesex and mab-3 related transcription factor 1 (DMRT1), basic helix-loop-helix transcription factor-like 5 (TCLF5), and octamer-binding transcription factor 4 (OCT4) in normal human spermatogenesis, testicular mixed germ cell-sex cord stromal tumor (MGC-SCST), spermatocytic tumor, and seminoma. "
4.	Neoplasms (Cancer) 12/01/2018 - "In the present study, we investigated protein expression of the transcription factors mammalian doublesex and mab-3 related transcription factor 1 (DMRT1), basic helix-loop-helix transcription factor-like 5 (TCLF5), and octamer-binding transcription factor 4 (OCT4) in normal human spermatogenesis, testicular mixed germ cell-sex cord stromal tumor (MGC-SCST), spermatocytic tumor, and seminoma. "
5.	Wilms Tumor (Wilm's Tumor) 01/01/2020 - "In this scenario, a differentiation model from mouse embryonic stem cells (mESCs) to eSCs was established through spatiotemporal control of 5 key factors, Wilms tumor 1 homolog (Wt1), GATA binding protein 4 (Gata4), nuclear receptor subfamily 5, group A, member 1 (Nr5a1, i.e., Sf1), SRY (sex determining region Y)-box 9 (Sox9), doublesex, and mab-3 related transcription factor 1 (Dmrt1). "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Basic Helix-Loop-Helix Transcription Factors
3.	Tretinoin (Retinoic Acid)
4.	Transcription Factors (Transcription Factor)
5.	Peptides (Polypeptides)
6.	Transcription Factor 4
7.	Retinoic Acid 4-Hydroxylase (CYP26B1)
8.	Cytochrome P450 Family 26
9.	R 115866
10.	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)