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1- phenyl- 2- hexadecanoylamino- 3- pyrrolidino- 1- propanol

inhibits glucosylceramide synthase; do not confuse with PPPP

Also Known As:

DL-threo-1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol; PPPP cpd

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Propanolamines: 4
      - 1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol: 1
- Alcohols: 595
  - Amino Alcohols: 20
    - Propanolamines: 4
      - 1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol: 1
  - Propanols: 3
    - Propanolamines: 4
      - 1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - 1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol: 1

Experts

1.	Deng, W: 1 article (06/2000)
2.	Ladisch, S: 1 article (06/2000)
3.	Li, R: 1 article (06/2000)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 06/07/2000 - "We tested a ganglioside-rich subline of B16 murine melanoma, MEB4, and MEB4 cells that had been depleted of endogenous gangliosides by incubation with 0.5 microM 1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol, a specific inhibitor of the enzyme glucosylceramide synthase. "

Related Drugs and Biologics

1.	Gangliosides
2.	Enzymes
3.	ceramide glucosyltransferase