HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

13B8-2 monoclonal antibody

binds to the Ig-CDR3-like loop in domain 1 of CD4

Also Known As:

13B8-2; MAb 13B8-2; monoclonal antibody 13B8-2

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        13B8-2 monoclonal antibody: 2
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        13B8-2 monoclonal antibody: 2
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        13B8-2 monoclonal antibody: 2

Related Diseases

1.

08/01/1999 - "In contrast, the HIV-1 envelope glycoprotein, gp120, and the two anti-CD4 mAbs, 13B8-2 and OKT4, were clearly active against HHV-7 infection."
12/15/1993 - "The presence of viral RNA was investigated and found in 13B8-2 mAb-treated CEM cells 30 min after viral exposure; the full-length viral DNA was found at 24 h post-infection. "
12/15/1993 - "We used the polymerase chain reaction (PCR) to study which step(s) of the human immunodeficiency virus type 1 (HIV-1) life cycle may be blocked following treatment of HIV-exposed CEM cells with 13B8-2, a monoclonal antibody (mAb) specific for the immunoglobulin (Ig) CDR3-like region of the CD4 molecule and able to inhibit the productive infection of CEM cells by HIV-1. "

Related Drugs and Biologics

1.	CD4 Antigens (CD4 Antigen)
2.	Immunoglobulins (Immunoglobulin)
3.	Monoclonal Antibodies
4.	Viral RNA
5.	Glycoproteins (Glycoprotein)
6.	Viral DNA