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13B8-2 monoclonal antibody
binds to the Ig-CDR3-like loop in domain 1 of CD4
Also Known As:
13B8-2; MAb 13B8-2; monoclonal antibody 13B8-2
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Blood Proteins: 12459
Serum Globulins: 553
Immunoglobulins: 30480
Antibodies: 133716
Monoclonal Antibodies: 56412
13B8-2 monoclonal antibody: 2
Immunoproteins: 43
Immunoglobulins: 30480
Antibodies: 133716
Monoclonal Antibodies: 56412
13B8-2 monoclonal antibody: 2
Globulins: 3062
Serum Globulins: 553
Immunoglobulins: 30480
Antibodies: 133716
Monoclonal Antibodies: 56412
13B8-2 monoclonal antibody: 2
Related Diseases
1.
Infections
08/01/1999 - "
In contrast, the HIV-1 envelope glycoprotein, gp120, and the two anti-CD4 mAbs, 13B8-2 and OKT4, were clearly active against HHV-7 infection.
"
12/15/1993 - "
The presence of viral RNA was investigated and found in 13B8-2 mAb-treated CEM cells 30 min after viral exposure; the full-length viral DNA was found at 24 h post-infection.
"
12/15/1993 - "
We used the polymerase chain reaction (PCR) to study which step(s) of the human immunodeficiency virus type 1 (HIV-1) life cycle may be blocked following treatment of HIV-exposed CEM cells with 13B8-2, a monoclonal antibody (mAb) specific for the immunoglobulin (Ig) CDR3-like region of the CD4 molecule and able to inhibit the productive infection of CEM cells by HIV-1.
"
Related Drugs and Biologics
1.
CD4 Antigens (CD4 Antigen)
2.
Immunoglobulins (Immunoglobulin)
3.
Monoclonal Antibodies
4.
Viral RNA
5.
Glycoproteins (Glycoprotein)
6.
Viral DNA