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4-aminophenylacetic acid

peptide mimic; structure in first source

Also Known As:

4-APAA

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - 4-aminophenylacetic acid: 3
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylacetates: 3
      - 4-aminophenylacetic acid: 3

Experts

1.	Ferreira, Lucas Franco: 1 article (01/2018)
2.	Pimenta, Thiago Coimbra: 1 article (01/2018)
3.	Santos, Cátia da Cruz: 1 article (01/2018)
4.	Thomasini, Ronaldo Luís: 1 article (01/2018)
5.	Ekwuribe, Nnochiri: 1 article (03/2005)
6.	Liddle, Rodger A: 1 article (03/2005)
7.	McVey, Douglas C: 1 article (03/2005)
8.	Riggs-Sauthier, Jennifer: 1 article (03/2005)
9.	Vigna, Steven R: 1 article (03/2005)

Related Diseases

1.	Inflammation (Inflammations) 03/01/2005 - "When 4-aminophenylacetic acid alone was administered chronically in drinking water, it also inhibited toxin A-induced colonic inflammation at a dose of 100 mg/kg x day. " 03/01/2005 - "It is concluded that APAZA is a potent inhibitor of toxin A-induced colonic inflammation in rats and that its constituent, 4-aminophenylacetic acid, is responsible for this increased protection against colitis compared to the 5-aminosalicylic acid component of sulfasalazine."
2.	Colitis 03/01/2005 - "4-Aminophenylacetic acid strongly and significantly inhibited toxin A-induced colitis in this experiment at doses as low as 10 microg/segment. " 03/01/2005 - "A new compound, APAZA, consisting of a molecule of 5-aminosalicylic acid linked to one molecule of 4-aminophenylacetic acid by an azo bond, was testedfor its ability to inhibit acute colitis in rats caused by Clostridium difficile toxin A. " 03/01/2005 - "It is concluded that APAZA is a potent inhibitor of toxin A-induced colonic inflammation in rats and that its constituent, 4-aminophenylacetic acid, is responsible for this increased protection against colitis compared to the 5-aminosalicylic acid component of sulfasalazine."
3.	Dengue (Dengue Fever) 01/01/2018 - "The present study aimed to develop an impedimetric immunosensor for dengue diagnosis using a screen-printed electrode (SPE) functionalized with polymer films derived from 4-aminophenylacetic acid (4-APA). "
4.	Inborn Urea Cycle Disorders 12/01/2023 - "In this manner, we generate three drug molecules in a single step: 4-aminophenylacetic acid (epithelial peptide transporter PepT1 inhibitor), 3,4-dihydroxyphenylacetic acid (dopamine metabolite neurotransmitter), and phenylacetic acid (sodium salt form; treatment of urea cycle disorder). "

Related Drugs and Biologics

1.	Mesalamine (Mesalazine)
2.	Sulfasalazine (Azulfidine)
3.	Polymers
4.	Drinking Water
5.	Neurotransmitter Agents (Neurotransmitter)
6.	3,4-Dihydroxyphenylacetic Acid
7.	Peptides (Polypeptides)
8.	Dopamine (Intropin)
9.	Clostridium difficile tcdA protein
10.	phenylacetic acid (phenylacetate)

Related Therapies and Procedures

1.	Electrodes (Electrode)