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N(omega)-propylarginine

inhibits neuronal nitrix oxide synthase; amino acid sequence in first source

Also Known As:

N(omega)-propyl-L-arginine; NPLA cpdn

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675

Experts

1.	Nagatani, Yoshinori: 1 article (03/2009)
2.	Ono, Hideki: 1 article (03/2009)
3.	Saitoh, Kazuya: 1 article (03/2009)
4.	Takasu, Keiko: 1 article (03/2009)
5.	Tanabe, Mitsuo: 1 article (03/2009)
6.	Baamonde, Ana: 1 article (07/2007)
7.	García, Verónica: 1 article (07/2007)
8.	Hidalgo, Agustín: 1 article (07/2007)
9.	Juárez, Lucía: 1 article (07/2007)
10.	Menéndez, Luis: 1 article (07/2007)

Related Diseases

1.	Reperfusion Injury 08/01/2004 - "The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle."
2.	Osteosarcoma (Osteogenic Sarcoma) 07/01/2007 - "The selective inhibitor of eNOS L-NIO, but not the inhibitors of nNOS (N-omega-propyl-L-arginine) or iNOS (1400w), blocked the effect of loperamide on osteosarcoma-induced hyperalgesia and also the endogenous opioid peripheral hypoalgesia that appears during the initial stages of the development of this osteosarcoma. "
3.	Neuralgia (Stump Neuralgia) 03/01/2009 - "Intrathecal injection of the NOS inhibitor N(G)-nitro-l-arginine methyl ester (l-NAME), the highly selective neuronal NOS (nNOS) inhibitor N(omega)-propyl-l-arginine and the potent selective inducible NOS (iNOS) inhibitor 2-amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride (AMT) exerted dose-dependent analgesic effects on thermal and mechanical hypersensitivity, which were assessed by the plantar and von Frey tests, respectively, suggesting that both nNOS and iNOS participate in producing NO to maintain neuropathic pain. "
4.	Hypersensitivity (Allergy) 03/01/2009 - "Intrathecal injection of the NOS inhibitor N(G)-nitro-l-arginine methyl ester (l-NAME), the highly selective neuronal NOS (nNOS) inhibitor N(omega)-propyl-l-arginine and the potent selective inducible NOS (iNOS) inhibitor 2-amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride (AMT) exerted dose-dependent analgesic effects on thermal and mechanical hypersensitivity, which were assessed by the plantar and von Frey tests, respectively, suggesting that both nNOS and iNOS participate in producing NO to maintain neuropathic pain. "
5.	Hyperalgesia 07/01/2007 - "The selective inhibitor of eNOS L-NIO, but not the inhibitors of nNOS (N-omega-propyl-L-arginine) or iNOS (1400w), blocked the effect of loperamide on osteosarcoma-induced hyperalgesia and also the endogenous opioid peripheral hypoalgesia that appears during the initial stages of the development of this osteosarcoma. "

Related Drugs and Biologics

1.	NG-Nitroarginine Methyl Ester (L-NAME)
2.	Loperamide (Imodium)
3.	Opioid Analgesics (Opioids)
4.	Analgesics (Analgesic Drugs)
5.	2- amino- 5,6- dihydro- 6- methyl- 4H- 1,3- thiazine
6.	N(G)-iminoethylornithine

Related Therapies and Procedures

1.	Spinal Injections