deoxyxylulose-5-phosphate synthase

catalyzes thiamin diphosphate-dependent acyloin condensation between pyruvate and glyceraldehyde

Also Known As:

1-deoxy-D-xylulose-5-phosphatase; 1-deoxy-D-xylulose-5-phosphate synthase; DXP synthase

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Bartee, David: 1 article (10/2018)
2.	Freel Meyers, Caren L: 1 article (10/2018)
3.	Battistini, Matthew R: 1 article (04/2016)
4.	Breydo, Leonid: 1 article (04/2016)
5.	Handa, Sumit: 1 article (04/2016)
6.	Merkler, David J: 1 article (04/2016)
7.	Shoji, Christopher: 1 article (04/2016)

1.	Infections 10/16/2018 - "Despite these challenges, the study of DXP synthase is poised to reveal the role of DXP synthase in bacterial metabolic adaptability during infection, ultimately providing a more complete picture of how inhibiting this crucial enzyme can be used to develop novel antibiotics."
2.	Malaria 04/01/2016 - "Mechanistic binding insights for 1-deoxy-D-Xylulose-5-Phosphate synthase, the enzyme catalyzing the first reaction of isoprenoid biosynthesis in the malaria-causing protists, Plasmodium falciparum and Plasmodium vivax."

1.	Enzymes
2.	Anti-Bacterial Agents (Antibiotics)
3.	Terpenes (Terpenoids)