polyozellin

isol from Polyozellus multiplex; inhibits prolyl endopeptidase; structure given in first source

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

1.	Neoplasms (Cancer) 02/11/2004 - "In conclusion, polyozellin deserves further in vivo study to evaluate its potential as a cancer preventive agent."
2.	Atopic Dermatitis (Atopic Eczema) 02/01/2020 - "This study aimed to determine the pharmacological effects of polyozellin on inflammatory and pruritic responses, the major symptoms of atopic dermatitis (AD), and to define its underlying mechanism of action. " 02/01/2020 - "Polyozellin alleviates atopic dermatitis-like inflammatory and pruritic responses in activated keratinocytes and mast cells."
3.	Lung Injury 04/01/2016 - "In addition, polyozellin suppressed cecal ligation and puncture-induced sepsis lethality and pulmonary injury. "
4.	Sepsis (Septicemia) 04/01/2016 - "In addition, polyozellin suppressed cecal ligation and puncture-induced sepsis lethality and pulmonary injury. "
5.	Inflammation (Inflammations) 01/01/2011 - "Collectively, these results suggest that polyozellin has the potential to attenuate intestinal inflammation and shed light on the novel signal pathway evoked by TNF-α during intestinal inflammation." 01/01/2011 - "Here we evaluated whether polyozellin has the potential to ameliorate diseases characterized by mucosal inflammation in intestinal epithelial HT-29 cells. "

1.	Enzymes