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argentilactone

from root of Annona haematantha; structure given in first source

Also Known As:

6-(1-Heptenyl)-5,6-dihydro-2H-pyran-2-one

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - argentilactone: 2

Experts

1.	Antônio, Márcia Aparecida: 1 article (10/2004)
2.	Kohn, Luciana Konecny: 1 article (10/2004)
3.	Pilli, Ronaldo Aloise: 1 article (10/2004)
4.	de Carvalho, João Ernesto: 1 article (10/2004)
5.	de Fatima, Angelo: 1 article (10/2004)

Related Diseases

1.	Cutaneous Leishmaniasis 10/01/1997 - "Experimental treatment of cutaneous leishmaniasis with argentilactone isolated from Annona haematantha."
2.	Neoplasms (Cancer) 10/15/2004 - "Concise total syntheses of (R)- and (S)-argentilactone have been developed via enantioselective catalytic allylation (ECA) and ring-closing metathesis pathways (four steps, 39% overall yield and 82-84% ee) from 2-octynal and their in vitro activity against cancer cells is described." 10/15/2004 - "Enantioselective syntheses of (R)- and (S)-argentilactone and their cytotoxic activities against cancer cell lines."
3.	Infections 10/01/1997 - "This compound exhibited in vitro activity against various strains of Leishmania ssp. at 10 micrograms/ml. BALB/c mice infected with Leishmania amazonensis were treated four weeks after infection with argentilactone by oral or subcutaneous routes for 14 days at 25 mg/kg daily. "

Related Drugs and Biologics

1.	Dihydrotachysterol (AT 10)