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NNC 05-2045

Also Known As:

1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(4-methoxyphenyl)-4-piperidinol; NNC-05-2045

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - NNC 05-2045: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Carbazoles: 32
        NNC 05-2045: 1
  - 3-Ring Heterocyclic Compounds
    - Carbazoles: 32
      - NNC 05-2045: 1

Related Diseases

1.	Seizures (Absence Seizure) 07/01/1997 - "In amygdala kindled rats NNC 05-2045 and NNC 05-2090 significantly (P < 0.05) reduced generalized seizure severity (seizure grade 3-5) at highest doses (72-242 mumol/kg) and NNC 05-2090 also significantly reduced afterdischarge duration at these doses (P < 0.05). " 07/01/1997 - "NNC 05-2045 also antagonized sound-induced seizures in genetic epilepsy prone rats (GEP rats) with ED50 values against wild running, clonic and tonic convulsions of 33, 39 and 39 mumol/kg, respectively (NNC 05-2090 was not tested in GEP rats). "
2.	Epilepsy (Aura) 07/01/1997 - "NNC 05-2045 also antagonized sound-induced seizures in genetic epilepsy prone rats (GEP rats) with ED50 values against wild running, clonic and tonic convulsions of 33, 39 and 39 mumol/kg, respectively (NNC 05-2090 was not tested in GEP rats). "

Related Drugs and Biologics

1.	NNC 05-2090