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T 477

structure in first source

Also Known As:

2-(4-chlorophenyl)-2,3-dihydro-4-diethylaminoacetyl-4H-1,4-benzothiazine; T-477

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazines: 3
    - T 477: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiazines: 3
    - T 477: 2

Experts

1.	Bolch, W: 1 article (06/2012)
2.	Cantley, J: 1 article (06/2012)
3.	Chell, E: 1 article (06/2012)
4.	Firpo, M: 1 article (06/2012)
5.	Hanlon, J: 1 article (06/2012)
6.	Lee, C: 1 article (06/2012)

Related Diseases

1.	Brain Edema (Cerebral Edema) 10/01/1999 - "The present study was undertaken to evaluate the effect of T-477 [(R)-(+)-2-(4-chlorophenyl)-2,3-dihydro-4-diethyl aminoacetyl-4H-1,4-benzorthiazine hydrochloride], a novel neuronal Na+ and Ca2+ channel blocker, on brain edema in rats. " 10/01/1999 - "A novel Na+ and Ca2+ channel blocker, T-477, prevents brain edema following microsphere-induced permanent occlusion of cerebral arterioles in rats." 10/01/1999 - "In conclusion, T-477 prevents brain edema following microsphere-induced cerebral embolism in rats."
2.	Intracranial Embolism 10/01/1999 - "In conclusion, T-477 prevents brain edema following microsphere-induced cerebral embolism in rats."
3.	Macular Degeneration (Age-Related Maculopathy) 06/01/2012 - "SU-E-T-477: Influence of Eye Size on Radiation Absorbed Dose Delivered to Non- Targeted Tissues during Stereotactic Radiosurgery for Age-Related Macular Degeneration."

Related Therapies and Procedures

1.	Microspheres (Microsphere)